Skin Dermatology Institute, Tauranga, New Zealand; Bay of Plenty District Health Board, Department of Dermatology, Tauranga Hospital, Tauranga, New Zealand; Pathlab Bay of Plenty, Tauranga, New Zealand.
Australas J Dermatol. 2013 Nov;54(4):313-6. doi: 10.1111/ajd.12055. Epub 2013 May 8.
Elderly patients with extensive hypertrophic solar keratoses and squamous cell carcinoma on the lower legs can pose significant management challenges. Typically these patients require surgical treatment which is complicated by comorbidities and poor background lower leg skin. 5% fluorouracil chemowraps provides a useful alternative technique for the management of diffuse hypertrophic solar keratoses and as an adjuvant, and in some situations as a palliative treatment, for squamous cell carcinomas on the lower legs.
对于患有广泛肥厚性光化性角化病和下肢鳞状细胞癌的老年患者，管理起来具有很大的挑战性。这些患者通常需要手术治疗，但由于合并症和下肢皮肤状况不佳，手术治疗变得复杂。5%氟尿嘧啶化学敷贴是治疗弥漫性肥厚性光化性角化病的一种有用的替代技术，也可作为辅助手段，在某些情况下还可作为下肢鳞状细胞癌的姑息治疗手段。
