Lambert Thomas, Mullinax Kimberly, Smith Jennifer
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, USA.
J Drugs Dermatol. 2006 Mar;5(3):282-3.
A 73-year-old Caucasian male was treated in the dermatology clinic for squamous cell carcinoma (SCC) of the scalp by Mohs micrographic surgery. The patient subsequently received radiation therapy because of possible calvarium invasion. Approximately 2 years later, the patient developed Bowen's disease within the previously irradiated skin flap. The lesion was treated with topical 5-fluorouracil (5-FU) twice daily for 4 weeks, and subsequently developed a 2 x 2 cm full-thickness ulceration with exposed calvarium.
一名73岁的白种男性因头皮鳞状细胞癌在皮肤科诊所接受了莫氏显微外科手术治疗。随后，由于可能存在颅骨侵犯，该患者接受了放射治疗。大约2年后，患者在先前接受过放射治疗的皮瓣内发生了鲍温病。该病变每天外用5-氟尿嘧啶（5-FU）两次，持续4周，随后发展为一个2×2厘米的全层溃疡，颅骨外露。
