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坦桑尼亚农村获得青蒿素类抗疟治疗及其相关因素。

Access to artemisinin-based anti-malarial treatment and its related factors in rural Tanzania.

机构信息

Ifakara Health Institute, Dar es Salaam, Tanzania.

出版信息

Malar J. 2013 May 7;12:155. doi: 10.1186/1475-2875-12-155.

Abstract

BACKGROUND

Artemisinin-based combination treatment (ACT) has been widely adopted as one of the main malaria control strategies. However, its promise to save thousands of lives in sub-Saharan Africa depends on how effective the use of ACT is within the routine health system. The INESS platform evaluated effective coverage of ACT in several African countries. Timely access within 24 hours to an authorized ACT outlet is one of the determinants of effective coverage and was assessed for artemether-lumefantrine (Alu), in two district health systems in rural Tanzania.

METHODS

From October 2009 to June 2011 we conducted continuous rolling household surveys in the Kilombero-Ulanga and the Rufiji Health and Demographic Surveillance Sites (HDSS). Surveys were linked to the routine HDSS update rounds. Members of randomly pre-selected households that had experienced a fever episode in the previous two weeks were eligible for a structured interview. Data on individual treatment seeking, access to treatment, timing, source of treatment and household costs per episode were collected. Data are presented on timely access from a total of 2,112 interviews in relation to demographics, seasonality, and socio economic status.

RESULTS

In Kilombero-Ulanga, 41.8% (CI: 36.6-45.1) and in Rufiji 36.8% (33.7-40.1) of fever cases had access to an authorized ACT provider within 24 hours of fever onset. In neither of the HDSS site was age, sex, socio-economic status or seasonality of malaria found to be significantly correlated with timely access.

CONCLUSION

Timely access to authorized ACT providers is below 50% despite interventions intended to improve access such as social marketing and accreditation of private dispensing outlets. To improve prompt diagnosis and treatment, access remains a major bottle neck and new more innovative interventions are needed to raise effective coverage of malaria treatment in Tanzania.

摘要

背景

青蒿素类复方疗法(ACT)已被广泛采用,作为主要疟疾控制策略之一。然而,在撒哈拉以南非洲,ACT 要想拯救成千上万的生命,关键在于在常规卫生系统中 ACT 的使用效果如何。INESS 平台评估了几种非洲国家中 ACT 的有效覆盖率。在坦桑尼亚的两个农村地区卫生系统中,24 小时内及时获得授权的 ACT 服务点是有效覆盖率的决定因素之一,我们评估了青蒿琥酯-甲氟喹(Alu)的及时获得情况。

方法

从 2009 年 10 月至 2011 年 6 月,我们在基利莫罗-乌兰加和鲁菲吉卫生和人口监测点(HDSS)进行了连续滚动家庭调查。调查与常规 HDSS 更新回合相联系。在前两周经历过发热事件的随机预先选定家庭的成员有资格接受结构化访谈。收集了有关个体寻求治疗、获得治疗、时间、治疗来源和每个病例的家庭费用的数据。根据总共 2112 次访谈,介绍了在人口统计学、季节性和社会经济地位方面及时获得的情况。

结果

在基利莫罗-乌兰加,41.8%(95%置信区间:36.6-45.1)和鲁菲吉 36.8%(95%置信区间:33.7-40.1)的发热病例在发热发作后 24 小时内能够获得授权的 ACT 提供者。在这两个 HDSS 地点,年龄、性别、社会经济地位或疟疾季节性均未被发现与及时获得显著相关。

结论

尽管有改善获取途径的干预措施,如社会营销和私人配药服务点认证,但获得授权的 ACT 提供者的及时获得率仍低于 50%。为了改善及时诊断和治疗,获得途径仍然是一个主要的瓶颈,需要新的更具创新性的干预措施来提高坦桑尼亚疟疾治疗的有效覆盖率。

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