Sandler R S
Division of Digestive Diseases and Nutrition, University of North Carolina, Chapel Hill.
Gastroenterology. 1990 Aug;99(2):409-15. doi: 10.1016/0016-5085(90)91023-y.
Data from six large, systematic national health surveys were examined to provide a more complete description of the epidemiology of irritable bowel syndrome in the United States. Data from the Second National Health and Nutrition Examination Survey, 1976-1980, indicated 4.7 million people (2.9% of the population) with self-reported diagnoses of irritable bowel syndrome. Rates for women were 3.2 times those for men, and rates for whites were 5.3 times those for blacks. Rates were highest among those aged 45-64 years. More than 2.6 million (1.6% of the population) were symptomatic at the time of the survey. Data from the National Ambulatory Medical Care Survey, 1985, and the National Disease and Therapeutic Index, 1987, documented between 2.4 and 3.5 million yearly visits to physicians by patients with irritable bowel syndrome and more than 2.2 million medications prescribed. Rates of hospitalization for women have fallen from 71.9 (per 100,000 population) in 1982 to 21.1 in 1987 based on data from the National Hospital Discharge Survey. A similar pattern was observed in data from the Commission on Professional and Hospital Activities. The data support the impression that irritable bowel syndrome is a prevalent condition in the United States with significant impact on health care. Large-scale, population-based surveys using standard criteria are needed to estimate the true extent of irritable bowel syndrome.
对六项大型全国性系统健康调查的数据进行了研究，以更全面地描述美国肠易激综合征的流行病学情况。1976 - 1980年第二次全国健康与营养检查调查的数据显示，有470万人（占总人口的2.9%）自我报告诊断为肠易激综合征。女性患病率是男性的3.2倍，白人患病率是黑人的5.3倍。患病率在45 - 64岁人群中最高。在调查时，超过260万人（占总人口的1.6%）有症状。1985年全国门诊医疗调查和1987年全国疾病与治疗指数的数据表明，肠易激综合征患者每年看医生的次数在240万至350万之间，开出的药物超过220万剂。根据全国医院出院调查的数据，女性住院率从1982年的71.9（每10万人）降至1987年的21.1。专业与医院活动委员会的数据也观察到类似模式。这些数据支持了肠易激综合征在美国是一种普遍疾病且对医疗保健有重大影响的观点。需要采用标准标准进行大规模的基于人群的调查来估计肠易激综合征的真实程度。
