胸主动脉夹层腔内修复术后围手术期夹层破裂:治疗 B 型夹层。
Perioperative aortic dissection rupture after endovascular stent graft placement for treatment of type B dissection.
机构信息
Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China.
出版信息
Chin Med J (Engl). 2013;126(9):1636-41.
BACKGROUND
The perioperative aortic dissection (AD) rupture is a severe event after endovascular stent graft placement for treatment of type B AD. However, this life-threatening complication has not undergone systematic investigation. The aim of the study is to discuss the reasons of AD rupture after the procedure.
METHODS
The medical record data of 563 Stanford type B AD patients who received thoracic endovascular repair from 2004 to December 2011 at our institution were collected and analyzed. Double entry and consistency checking were performed with Epidata software.
RESULTS
Twelve patients died during the perioperation after thoracic endovascular repair, with an incidence of 2.1%, 66.6% were caused by aortic rupture and half of the aortic rupture deaths were caused by retrograde type A AD. In our study, 74% of the non-rupture surviving patients had the free-flow bare spring proximal stent implanted, compared with 100% of the aortic rupture patients (74% vs. 100%, P = 0.213). The aortic rupture patients are more likely to have ascending aortic diameters = 4 cm (62.5% vs. 9.0%, P = 0.032), involvement the aortic arch concavity (62% vs. 27%, P = 0.041) and have had multiple stents placed (P = 0.039).
CONCLUSIONS
Thoracic AD endovascular repair is a safe and effective treatment option for AD with relative low in-hospital mortality. AD rupture may be more common in arch stent-graft patients with an ascending aortic diameter = 4 cm and with severe dissection that needs multi-stent placement. Attention should be paid to a proximal bare spring stent that has a higher probability of inducing an AD rupture. Post balloon dilation should be performed with serious caution, particularly for the migration during dilation.
背景
腔内修复术治疗 B 型主动脉夹层(AD)后围手术期 AD 破裂是一种严重事件。然而,这种危及生命的并发症尚未经过系统研究。本研究旨在探讨腔内修复术后 AD 破裂的原因。
方法
回顾性分析 2004 年 12 月至 2011 年 12 月我院 563 例接受胸主动脉腔内修复术的 Stanford 型 B 型 AD 患者的病历资料。采用 Epidata 软件进行双录入和一致性检查。
结果
胸主动脉腔内修复术后 12 例患者围手术期死亡,发生率为 2.1%,其中 66.6%由主动脉破裂引起,半数主动脉破裂死亡由逆行型 A 型 AD 引起。本研究中,74%未发生破裂的存活患者植入了自由血流裸支架,而主动脉破裂患者为 100%(74%比 100%,P=0.213)。主动脉破裂患者升主动脉直径≥4cm(62.5%比 9.0%,P=0.032)、主动脉弓凹陷受累(62%比 27%,P=0.041)和放置多个支架的可能性更高(P=0.039)。
结论
胸主动脉 AD 腔内修复术是治疗 AD 的一种安全有效的方法,院内死亡率相对较低。AD 破裂可能更常见于升主动脉直径≥4cm、严重夹层需要多支架置入的弓部支架患者。应注意近端裸支架有较高的 AD 破裂风险。球囊扩张后应谨慎进行,尤其是扩张过程中的移位。