Wang Xiang, Li Wei-Qing, Yan Hong-Zhu, Li Yi-Ming, He Jin, Liu Hui-Min, Yu Hong-Yu
Department of Neurosurgery, Changzheng Hospital, The Second Military Medical University, Shanghai, China.
J Int Med Res. 2013 Jun;41(3):895-906. doi: 10.1177/0300060513477304. Epub 2013 May 7.
Alveolar adenoma is an extremely rare and benign pulmonary neoplasm; it is always asymptomatic and is usually detected incidentally on routine chest X-radiography. Typically on imaging examinations, alveolar adenoma exhibits as a peripheral, solitary, cystic nodule in the lung, which may easily imitate other lung lesions, consequently leading to difficulties in the differential diagnosis of this condition. Surgical resection is the primary treatment option. The diagnosis of alveolar adenoma is mainly based on postoperative histopathology, with features of proliferative type 2 alveolar epithelial cells and septal mesenchyme. The present case was a 60-year-old woman with alveolar adenoma, combined with systemic mutifocal cystic lesions. She underwent surgery following the obvious enlargement of this mass and a cystic nodule 7 cm in maximum diameter was resected. Postoperative histopathology confirmed a diagnosis of alveolar adenoma; her prognosis was favourable. In addition to reporting a rare case of alveolar adenoma coexisting with multifocal cysts, the English-language literature was reviewed for similar cases of alveolar adenoma.
肺泡腺瘤是一种极其罕见的良性肺肿瘤；它通常无症状，常在常规胸部X线检查时偶然发现。在影像学检查中，肺泡腺瘤典型地表现为肺部外周的孤立性囊性结节，这可能很容易与其他肺部病变相混淆，从而导致该病的鉴别诊断困难。手术切除是主要的治疗选择。肺泡腺瘤的诊断主要基于术后组织病理学检查，其特征为2型肺泡上皮细胞和间隔间充质的增生。本病例为一名60岁患有肺泡腺瘤的女性，合并全身多灶性囊性病变。在该肿块明显增大后，她接受了手术，切除了一个最大直径为7厘米的囊性结节。术后组织病理学确诊为肺泡腺瘤；她的预后良好。除了报告一例罕见的肺泡腺瘤合并多灶性囊肿病例外，还对英文文献中类似的肺泡腺瘤病例进行了综述。
