Department of Pathology, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Pathologica. 2022 Aug;114(4):326-331. doi: 10.32074/1591-951X-755.
Alveolar adenoma is a rare tumour of the lung. It is typically found in asymptomatic adults as a peripheral or subplerual nodule on imaging examination. Microscopically, the tumour is composed of admixture of epithelial and mesenchymal component in variable sized cystic or alveolar structures. The tumour shows a benign nature. There have been no reported recurrences or metastases. Malignant transformation of alveolar adenoma and coexisting with lung carcinoma have been rarely described. In this article, we report a case of an alveolar adenoma and coexisting atypical adenomatous hyperplasia. This case, contributing to the limited numbers of cases described to date, illustrates the importance of awareness on the possibility of alveolar adenoma being associated with lung carcinoma and its precursor lesions especially when diagnosed by small biopsy specimens.
肺泡腺瘤是一种罕见的肺部肿瘤。它通常在无症状的成年人中作为影像学检查的外周或胸膜下结节发现。显微镜下，肿瘤由上皮和间充质成分的混合物组成，呈不同大小的囊性或肺泡结构。肿瘤表现为良性。尚未有复发或转移的报道。肺泡腺瘤的恶性转化和与肺癌共存很少被描述。本文报道了一例肺泡腺瘤合并非典型腺瘤样增生。该病例，增加了迄今为止描述的有限数量的病例，说明了肺泡腺瘤与肺癌及其前体病变相关的可能性的认识的重要性，特别是当通过小活检标本诊断时。
