Kamra Hemlata T, Dantkale Sunita S, Birla Khushboo, Sakinlawar Pankaj W, Bharia Paresh H
Department of Pathology, Government Medical College, Latur-413512, Maharashtra, India.
Ecancermedicalscience. 2013 May 2;7:313. doi: 10.3332/ecancer.2013.313. Print 2013.
Plexiform neurofibroma is more commonly seen in the orbit, neck, back, and inguinal region. It is extremely rare in the submandibular gland. These lesions rarely transform into malignancy but are locally infiltrative and can lead to haemorrhage. Therefore, plexiform neurofibroma should always be considered during differential diagnosis while excising a submandibular gland mass. We present here a case of plexiform neurofibroma in the submandibular gland and diffuse neurofibroma in the floor of the mouth in a 27-year-old female, not associated with neurofibromatosis-1.
丛状神经纤维瘤多见于眼眶、颈部、背部和腹股沟区。在颌下腺极为罕见。这些病变很少恶变,但具有局部浸润性,可导致出血。因此,在切除颌下腺肿块进行鉴别诊断时,应始终考虑丛状神经纤维瘤。我们在此报告一例27岁女性颌下腺丛状神经纤维瘤及口底弥漫性神经纤维瘤病例,该病例与1型神经纤维瘤病无关。