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下颌下腺丛状神经纤维瘤伴口腔底部小的弥漫性神经纤维瘤，无1型神经纤维瘤病：一例罕见病例报告

Plexiform neurofibroma in the submandibular gland along with small diffuse neurofibroma in the floor of the mouth but without neurofibromatosis-1: a rare case report.

作者信息

Kamra Hemlata T, Dantkale Sunita S, Birla Khushboo, Sakinlawar Pankaj W, Bharia Paresh H

机构信息

Department of Pathology, Government Medical College, Latur-413512, Maharashtra, India.

出版信息

Ecancermedicalscience. 2013 May 2;7:313. doi: 10.3332/ecancer.2013.313. Print 2013.

DOI:10.3332/ecancer.2013.313
PMID:23653673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3634724/
Abstract

Plexiform neurofibroma is more commonly seen in the orbit, neck, back, and inguinal region. It is extremely rare in the submandibular gland. These lesions rarely transform into malignancy but are locally infiltrative and can lead to haemorrhage. Therefore, plexiform neurofibroma should always be considered during differential diagnosis while excising a submandibular gland mass. We present here a case of plexiform neurofibroma in the submandibular gland and diffuse neurofibroma in the floor of the mouth in a 27-year-old female, not associated with neurofibromatosis-1.

摘要

丛状神经纤维瘤多见于眼眶、颈部、背部和腹股沟区。在颌下腺极为罕见。这些病变很少恶变，但具有局部浸润性，可导致出血。因此，在切除颌下腺肿块进行鉴别诊断时，应始终考虑丛状神经纤维瘤。我们在此报告一例27岁女性颌下腺丛状神经纤维瘤及口底弥漫性神经纤维瘤病例，该病例与1型神经纤维瘤病无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/7c13ab922e08/can-7-313fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/1f8a9477cfa1/can-7-313fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/d80823b7722b/can-7-313fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/9a837328632f/can-7-313fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/5b846442195b/can-7-313fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/4956b3b47ee8/can-7-313fig5a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/8ee774df5e25/can-7-313fig5b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/98159ada6d1f/can-7-313fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/0ad5b3e27ac4/can-7-313fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/7c13ab922e08/can-7-313fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/1f8a9477cfa1/can-7-313fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/d80823b7722b/can-7-313fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/9a837328632f/can-7-313fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/5b846442195b/can-7-313fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/4956b3b47ee8/can-7-313fig5a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/8ee774df5e25/can-7-313fig5b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/98159ada6d1f/can-7-313fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/0ad5b3e27ac4/can-7-313fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab10/3634724/7c13ab922e08/can-7-313fig8.jpg

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本文引用的文献

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2
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J Pediatr. 2012 Mar;160(3):461-7. doi: 10.1016/j.jpeds.2011.08.051. Epub 2011 Oct 11.
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Plexiform neurofibroma of the submandibular gland in patient with von Recklinghausen's disease.患有冯雷克林霍增氏病患者的下颌下腺丛状神经纤维瘤。
孤立性非综合征性口腔丛状神经纤维瘤：一例报告并文献复习
J Dent (Shiraz). 2016 Sep;17(3 Suppl):293-296.
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Oral plexiform neurofibroma not associated with neurofibromatosis type I: case report.不伴有I型神经纤维瘤病的口腔丛状神经纤维瘤：病例报告
J Oral Sci. 2006 Sep;48(3):157-60. doi: 10.2334/josnusd.48.157.
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