质子化多核苷酸结构。16. 聚胞苷酸酸形式的熔解热力学。
Protonated polynucleotide structures. 16. Thermodynamics of the melting of the acid form of polycytidylic acid.
作者信息
Guschlbauer W
出版信息
Nucleic Acids Res. 1975 Mar;2(3):353-60. doi: 10.1093/nar/2.3.353.
Abstract
A phase diagram (pH, ionic strength, temperature) for the double helical form of poly(C) is presented. The thermo-dynamic analysis of these data shows that poly(C) behaves essentially as cytidine, if the electrostatic (ionic strength) contributions and the free energy of double helix formation are considered and taken into account.
摘要
给出了聚（C）双螺旋形式的相图（pH值、离子强度、温度）。对这些数据的热力学分析表明，如果考虑并计入静电（离子强度）贡献和双螺旋形成的自由能，聚（C）的行为本质上与胞苷相同。
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