Matarasso Sergio, Iorio Siciliano Vincenzo, Aglietta Marco, Andreuccetti Gianmaria, Salvi Giovanni E
Department of Periodontology, University Federico II, Naples, Italy.
Clin Oral Implants Res. 2014 Jul;25(7):761-7. doi: 10.1111/clr.12183. Epub 2013 May 8.
To assess the clinical and radiographic outcomes applying a combined resective and regenerative approach in the treatment of peri-implantitis.
Subjects with implants diagnosed with peri-implantitis (i.e., pocket probing depth (PPD) ≥5 mm with concomitant bleeding on probing (BoP) and ≥2 mm of marginal bone loss or exposure of ≥1 implant thread) were treated by means of a combined approach including the application of a deproteinized bovine bone mineral and a collagen membrane in the intrabony and implantoplasty in the suprabony component of the peri-implant lesion, respectively. The soft tissues were apically repositioned allowing for a non-submerged healing. Clinical and radiographic parameters were evaluated at baseline and 12 months after treatment.
Eleven subjects with 11 implants were treated and completed the 12-month follow-up. No implant was lost yielding a 100% survival rate. At baseline, the mean PPD and mean clinical attachment level (CAL) were 8.1 ± 1.8 mm and 9.7 ± 2.5 mm, respectively. After 1 year, a mean PPD of 4.0 ± 1.3 mm and a mean CAL of 6.7 ± 2.5 mm were assessed. The differences between the baseline and the follow-up examinations were statistically significant (P = 0.001). The mucosal recession increased from 1.7 ± 1.5 at baseline to 3.0 ± 1.8 mm at the 12-month follow-up (P = 0.003). The mean% of sites with BoP+ around the selected implants decreased from 19.7 ± 40.1 at baseline to 6.1 ± 24.0 after 12 months (P = 0.032). The radiographic marginal bone level decreased from 8.0 ± 3.7 mm at baseline to 5.2 ± 2.2 mm at the 12-month follow-up (P = 0.000001). The radiographic fill of the intrabony component of the defect amounted to 93.3 ± 13.0%.
Within the limits of this study, a combined regenerative and resective approach for the treatment of peri-implant defects yielded positive outcomes in terms of PPD reduction and radiographic defect fill after 12 months.
评估采用切除与再生相结合的方法治疗种植体周围炎的临床和影像学效果。
对诊断为种植体周围炎的患者（即探诊深度（PPD）≥5 mm且伴有探诊出血（BoP）以及边缘骨丧失≥2 mm或至少1个种植体螺纹暴露）采用联合治疗方法，分别在种植体周围病变的骨内部分应用脱蛋白牛骨矿物质，在骨上部分进行种植体成形术并使用胶原膜。将软组织向根尖方向复位以实现非潜入式愈合。在基线和治疗后12个月评估临床和影像学参数。
11名患者的11颗种植体接受治疗并完成了12个月的随访。无种植体丢失，生存率为100%。基线时，平均PPD和平均临床附着水平（CAL）分别为8.1±1.8 mm和9.7±2.5 mm。1年后，评估的平均PPD为4.0±1.3 mm，平均CAL为6.7±2.5 mm。基线检查与随访检查之间的差异具有统计学意义（P = 0.001）。黏膜退缩从基线时的1.
