Bonnette E D, Kornegay E T, Lindemann M D, Notter D R
Virginia Polytechnic Institute and State University, Blacksburg 24061.
J Anim Sci. 1990 May;68(5):1346-53. doi: 10.2527/1990.6851346x.
Three trials using 156 Yorkshire x Hampshire x Duroc crossbred pigs (avg initial wt, 7.9 kg) were conducted to evaluate the effects of two supplemental dietary vitamin E (11 vs 220 IU/kg of diet) and weaning age (21, 28 or 35 d) on performance and immunocompetence of pigs. Supplemental vitamin E (220 IU/kg of diet) increased (P less than .01) serum concentrations of vitamin E for all weaning ages compared with pigs fed 11 IU of vitamin E/kg of diet. However, supplemental vitamin E did not affect performance, serum cortisol concentration or the primary and secondary antibody response to sheep red blood cells. As weaning age increased, weekly ADG and avg daily feed intake increased linearly (P less than .01). Cortisol levels decreased during the 1st wk following weaning and then increased linearly (P less than .01) over time; pigs weaned at 35 d of age had higher (P less than .01) cortisol values initially and over time than pigs weaned at 21 and 28 d. Pigs weaned at 35 d had a higher (P less than .01) primary response to sheep red blood cells than pigs weaned at 21 and 28 d of age, but this effect was not observed for the secondary response. There were no interactive effects (P greater than .10) of dietary vitamin E level and weaning age. In summary, the highest level of supplemental vitamin E increased serum vitamin E concentration but did not affect performance, cortisol levels or one test of the immune response, antibody titers to red blood cells.(ABSTRACT TRUNCATED AT 250 WORDS)
采用156头约克夏×汉普夏×杜洛克杂交猪（初始平均体重7.9千克）进行了三项试验，以评估两种日粮维生素E添加量（11与220国际单位/千克日粮）和断奶日龄（21、28或35日龄）对猪生长性能和免疫能力的影响。与采食11国际单位维生素E/千克日粮的猪相比，添加维生素E（220国际单位/千克日粮）使所有断奶日龄猪的血清维生素E浓度升高（P<0.01）。然而，添加维生素E对生长性能、血清皮质醇浓度或对绵羊红细胞的初次和二次抗体反应没有影响。随着断奶日龄增加，每周平均日增重和平均日采食量呈线性增加（P<0.01）。皮质醇水平在断奶后的第1周下降，然后随时间呈线性增加（P<0.01）；35日龄断奶的猪在初始和整个时间段的皮质醇值均高于21日龄和28日龄断奶的猪（P<0.01）。35日龄断奶的猪对绵羊红细胞的初次反应高于21日龄和28日龄断奶的猪（P<0.01），但二次反应未观察到这种效应。日粮维生素E水平和断奶日龄之间没有交互作用（P>0.10）。总之，最高水平的维生素E添加量增加了血清维生素E浓度，但对生长性能、皮质醇水平或一项免疫反应测试（红细胞抗体滴度）没有影响。（摘要截短至250字）
