Wilde A H, Schickendantz M S, Stulberg B N, Go R T
Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Ohio 44195-5027.
J Bone Joint Surg Am. 1990 Jul;72(6):815-24.
Twelve knees in ten patients had revision total knee replacement with insertion of an allograft for a large tibial defect. The knees were retrospectively evaluated at an average of thirty-two months (range, twenty-five to fifty-one months) by clinical examination, radiography, planar bone scintigraphy, and single-photon-emission computed tomography. The average age of the patients was sixty-two years (range, fifty-four to seventy-nine years). A constrained total-condylar prosthesis was used for all revisions. A contained tibial defect was present in five knees, and seven knees had an uncontained defect that was treated with a massive composite structural allograft, five of which were secured with internal fixation. The knee scores improved from an average of 51 points before operation to an average of 87 points post-operatively. Seven knees had a score of 85 points or more and were considered to have an excellent clinical result. Two knees had a good result, with scores of 77 and 72 points. One knee had another revision because of painful non-union of a medial structural graft, and the result in that knee was considered a failure. The average range of motion improved from 84 degrees to 105 degrees. There were no deep infections, and no graft showed evidence of fracture or collapse. Radiographs demonstrated complete incorporation of the graft in eleven of the twelve knees at an average of twenty-three months after operation. Single-photon-emission computed-tomography scans showed uniform activity in the area of the graft in four of the five knees that were studied.
10名患者的12个膝关节接受了全膝关节置换翻修术,术中植入同种异体骨以修复较大的胫骨缺损。通过临床检查、X线摄影、平面骨闪烁显像及单光子发射计算机断层扫描对这些膝关节进行了平均32个月(范围为25至51个月)的回顾性评估。患者的平均年龄为62岁(范围为54至79岁)。所有翻修手术均使用了限制性全髁假体。5个膝关节存在局限性胫骨缺损,7个膝关节存在非局限性缺损,采用大块复合结构性同种异体骨进行治疗,其中5个用内固定进行固定。膝关节评分从术前的平均51分提高到术后的平均87分。7个膝关节评分达到85分或更高,被认为临床结果极佳。2个膝关节结果良好,评分为77分和72分。1个膝关节因内侧结构性移植骨疼痛性骨不连而再次翻修,该膝关节的结果被认为是失败的。平均活动范围从84度提高到105度。未发生深部感染,且没有移植骨出现骨折或塌陷的迹象。X线片显示,术后平均23个月时,12个膝关节中有11个的移植骨已完全融合。单光子发射计算机断层扫描显示,在接受研究的5个膝关节中,有4个膝关节移植骨区域的活性均匀。