1Clinic of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
Angiology. 2014 Feb;65(2):154-9. doi: 10.1177/0003319713488930. Epub 2013 May 8.
Admission hyperglycemia is associated with high inhospital and long-term adverse events in patients that undergo primary percutaneous coronary intervention (PCI). We aimed to evaluate whether hyperglycemia predicts inhospital mortality. We prospectively analyzed 503 consecutive patients. The patients were divided into tertiles according to the admission glucose levels. Tertile I: glucose <118 mg/dL (n = 166), tertile II: glucose 118 to 145 mg/dL (n = 168), and tertile III: glucose >145 mg/dL (n = 169). Inhospital mortality was 0 in tertile I, 2 in tertile II, and 9 in tertile III (P < .02). Cardiogenic shock occurred more frequently in tertile III compared to tertiles I and II (10% vs 4.1% and 0.6%, respectively, P = .01). Multivariate logistic regression analysis revealed that patients in tertile III had significantly higher risk of inhospital major adverse cardiac events compared to patients in tertile I (odds ratio: 9.55, P < .02). Admission hyperglycemia predicts inhospital adverse cardiac events in mortality and acute ST-segment elevation myocardial infarction in patients that underwent primary PCI.
入院时的高血糖与行直接经皮冠状动脉介入治疗（PCI）的患者住院期间和长期的不良事件有关。我们旨在评估高血糖是否可以预测住院期间的死亡率。我们前瞻性地分析了 503 例连续患者。根据入院时的血糖水平，患者被分为三分位。三分位 I：血糖 <118mg/dL（n = 166）；三分位 II：血糖 118 至 145mg/dL（n = 168）；三分位 III：血糖 >145mg/dL（n = 169）。三分位 I 患者住院期间死亡率为 0，三分位 II 患者为 2，三分位 III 患者为 9（P <.02）。与三分位 I 和 II 相比，三分位 III 患者发生心源性休克的频率更高（分别为 10%、4.1%和 0.6%，P =.01）。多变量逻辑回归分析显示，与三分位 I 患者相比，三分位 III 患者住院期间发生主要不良心脏事件的风险显著更高（比值比：9.55，P <.02）。在直接 PCI 治疗的患者中，入院时的高血糖可预测住院期间死亡率和急性 ST 段抬高型心肌梗死的不良心脏事件。
