Brighenti Fernanda Lourenção, Takeshita Eliana Mitsue, Sant'ana Camila de Oliveira, Buzalaf Marília Afonso Rabelo, Delbem Alberto Carlos Botazzo
Department of Pediatric Dentistry, Araçatuba Dental School, Univ Estadual Paulista, Araçatuba, SP, Brazil.
Braz Dent J. 2013;24(1):35-9. doi: 10.1590/0103-6440201301995.
This study evaluated the capacity of fluoride acidic dentifrices (pH 4.5) to promote enamel remineralization using a pH cycling model, comparing them with a standard dentifrice (1,100 µgF/g). Enamel blocks had their surface polished and surface hardness determined (SH). Next, they were submitted to subsurface enamel demineralization and to post-demineralization surface hardness analysis. The blocks were divided into 6 experimental groups (n=10): placebo (without F, pH 4.5, negative control), 275, 412, 550, 1,100 µgF/g and a standard dentifrice (positive control). The blocks were submitted to pH cycling for 6 days and treatment with dentifrice slurries twice a day. After pH cycling, surface and cross-sectional hardness were assessed to obtain the percentage of surface hardness recovery (%SHR) and the integrated loss of subsurface hardness (ΔKHN). The results showed that %SHR was similar among acidic dentifrices with 412, 550, 1,100 µgF/g and to the positive control (Tukey's test; p>0.05). For ΔKHN, the acidic dentifrice with 550 µg F/g showed a better performance when compared with the positive control. It can be concluded that acidic dentifrice 550 µgF/g had similar remineralization capacity to that of positive control.
本研究使用pH循环模型评估了酸性含氟牙膏(pH 4.5)促进牙釉质再矿化的能力,并将其与标准牙膏(1100μgF/g)进行比较。牙釉质块经过表面抛光并测定表面硬度(SH)。接下来,对其进行牙釉质表层下脱矿处理,并进行脱矿后表面硬度分析。将这些牙釉质块分为6个实验组(n = 10):安慰剂组(不含氟,pH 4.5,阴性对照)、275μgF/g组、412μgF/g组、550μgF/g组、1100μgF/g组和标准牙膏组(阳性对照)。将牙釉质块进行6天的pH循环,每天用牙膏浆液处理两次。pH循环后,评估表面和横截面硬度,以获得表面硬度恢复百分比(%SHR)和表层下硬度的综合损失(ΔKHN)。结果表明,含412μgF/g、550μgF/g和1100μgF/g的酸性牙膏与阳性对照的%SHR相似(Tukey检验;p>0.05)。对于ΔKHN,与阳性对照相比,含550μgF/g的酸性牙膏表现更好。可以得出结论,含550μgF/g的酸性牙膏具有与阳性对照相似的再矿化能力。