酸性含氟牙膏有效性的体外评估

In vitro evaluation of the effectiveness of acidic fluoride dentifrices.

作者信息

Alves K M R P, Pessan J P, Brighenti F L, Franco K S, Oliveira F A L, Buzalaf M A R, Sassaki K T, Delbem A C B

机构信息

Araçatuba Dental School, UNESP-São Paulo State University, Araçatuba, SP, Brazil.

出版信息

Caries Res. 2007;41(4):263-7. doi: 10.1159/000101915.

DOI:10.1159/000101915

PMID:17556835

Abstract

This study evaluated the effectiveness of acidic low-fluoride dentifrices compared to conventional neutral dentifrices. Enamel blocks were submitted to pH cycling and treatment with slurries of dentifrices containing 0, 275, 412, 550 and 1,100 microg F/g (pH 4.5 or 7.0), and also a commercial dentifrice (1,100 microg F/g) and a commercial children's dentifrice (500 mug F/g). Variations in surface microhardness and in the mineral content in enamel after pH cycling were calculated. Enamel blocks treated with acidic dentifrices exhibited less mineral loss compared to neutral dentifrices (ANOVA; p < 0.05). The acidic dentifrices with 412 and 550 microg F/g had the same effectiveness as the neutral 1,100-microg F/g dentifrice and commercial 1,100-microg F/g dentifrice.

摘要

本研究评估了酸性低氟牙膏与传统中性牙膏相比的有效性。将牙釉质块进行pH循环处理，并用含0、275、412、550和1100μg F/g（pH 4.5或7.0）的牙膏浆液进行处理，还使用了一种市售牙膏（1100μg F/g）和一种市售儿童牙膏（500μg F/g）。计算了pH循环后牙釉质表面显微硬度和矿物质含量的变化。与中性牙膏相比，用酸性牙膏处理的牙釉质块矿物质损失更少（方差分析；p<0.05）。含412和550μg F/g的酸性牙膏与含1100μg F/g的中性牙膏和市售含1100μg F/g的牙膏具有相同的效果。