2nd Prop. Department of Internal Medicine, Aristotle University, Thessaloniki, Greece.
Andrology. 2013 Jul;1(4):556-62. doi: 10.1111/j.2047-2927.2013.00094.x. Epub 2013 May 8.
Traditional cardiovascular risk factors have been acknowledged as major contributors to sexual dysfunction in the general population. The purpose of this study was to explore their impact on sexual function in rheumatologic patients. A total of 557 consecutive rheumatologic patients, 449 females and 108 males, had their sexual function evaluated with the Female Sexual Functioning Index (FSFI) and the International Index of Erectile Function (IIEF) questionnaire respectively. Personal data regarding presence of cardiovascular risk factors were collected and analysed in association with the FSFI and IIEF scores. Mean age of the participants was 54.1 ± 14.1 years, mean body mass index was 27.5 ± 5.29 and mean systolic and diastolic blood pressure was 130.5 ± 19.82 and 79.5 ± 10.51 mmHg respectively. Hypertension was present in 39% of the participants, diabetes mellitus in 10.2%, dyslipidaemia in 33.6% and history of cardiovascular events in 8.6%, whereas smoking was recorded by 28.4% and alcohol consumption by 7.4%. Sexual dysfunction affected 68.6% of our study population (73.5% of females and 48.1% of males, p < 0.001). Logistic regression analysis revealed that age was the only factor associated with a significantly higher prevalence of sexual dysfunction (p < 0.001 for both genders, p = 0.013 in males and p < 0.001 in females). Increased age was identified as the only independent predictor of sexual dysfunction in our population. Apart from age, traditional cardiovascular risk factors failed to explain the increased prevalence of sexual dysfunction in these patients. Other contributing factors (physical and/or psychological) might account for the increased occurrence of sexual dysfunction in rheumatic disorders.
传统心血管危险因素已被公认为导致普通人群性功能障碍的主要因素。本研究旨在探讨其对风湿患者性功能的影响。共评估了 557 例连续风湿患者的性功能，其中 449 例女性和 108 例男性，分别使用女性性功能指数（FSFI）和国际勃起功能指数（IIEF）问卷进行评估。收集并分析了与 FSFI 和 IIEF 评分相关的心血管危险因素的个人数据。参与者的平均年龄为 54.1 ± 14.1 岁，平均体重指数为 27.5 ± 5.29，平均收缩压和舒张压分别为 130.5 ± 19.82 和 79.5 ± 10.51mmHg。39%的参与者存在高血压，10.2%患有糖尿病，33.6%存在血脂异常，8.6%有心血管事件史，28.4%有吸烟史，7.4%有饮酒史。性功能障碍影响了我们研究人群的 68.6%（女性为 73.5%，男性为 48.1%，p<0.001）。Logistic 回归分析显示，年龄是唯一与性功能障碍发生率显著相关的因素（p<0.001，男女均如此，p=0.013 仅男性，p<0.001 仅女性）。年龄的增加被确定为我们人群性功能障碍的唯一独立预测因素。除了年龄之外，传统心血管危险因素无法解释这些患者性功能障碍发生率的增加。其他致病因素（身体和/或心理）可能导致风湿性疾病中性功能障碍的发生率增加。
