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对数线性模型、性行为与艾滋病病毒:异性传播的流行病学意义

Loglinear models, sexual behavior and HIV: epidemiological implications of heterosexual transmission.

作者信息

Blower S M, Anderson R M, Wallace P

机构信息

Department of Pure and Applied Biology, Imperial College of Science, Technology and Medicine, London, U.K.

出版信息

J Acquir Immune Defic Syndr (1988). 1990;3(8):763-72.

PMID:2366147
Abstract

An analysis is presented of sexual behaviour data from a "random" sample (n = 780) of the adult population of England and Wales. Sex stratified frequency distributions of the reported number of sex partners/time were analysed for heterosexuals, demographic characteristics associated with the number of sex partners/time were identified, and epidemiological parameters (the basic reproductive rate of HIV and the doubling time of the epidemic) were calculated. These analyses suggest that the size of the group at risk for acquiring the virus by heterosexual transmission may be large and that the age of first sexual intercourse (for males and females) is decreasing in younger cohorts. Members of the potential heterosexual at-risk group may be identified by demographic variables such as marital status (males and females) and age (females only), but not by socioeconomic class. The epidemiological implications of our results for the heterosexual transmission of HIV are discussed.

摘要

本文对来自英格兰和威尔士成年人口“随机”样本(n = 780)的性行为数据进行了分析。分析了异性恋者按性别分层的性伴侣数量/时间报告频率分布,确定了与性伴侣数量/时间相关的人口统计学特征,并计算了流行病学参数(艾滋病毒的基本繁殖率和疫情倍增时间)。这些分析表明,通过异性传播感染病毒的高危人群规模可能很大,而且(男性和女性)首次性行为的年龄在较年轻队列中呈下降趋势。潜在的异性高危人群成员可通过人口统计学变量(如婚姻状况(男性和女性)和年龄(仅女性))来识别,但不能通过社会经济阶层来识别。本文讨论了我们的结果对艾滋病毒异性传播的流行病学意义。

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