伊朗西南部热带地区最常见的气传过敏原。
The most common aeroallergens in a tropical region in Southwestern Iran.
机构信息
Immunology department, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran.
出版信息
World Allergy Organ J. 2013 Apr 4;6(1):7. doi: 10.1186/1939-4551-6-7.
BACKGROUND
Respiratory allergies are the most important public health issues in the world. They are caused by aeroallergens which play great role in pathogenesis of respiratory allergic diseases.
METHODS
The current study was conducted to evaluate the prevalence of positive skin test for various aeroallergens among allergic patients in Ahvaz, southwest Iran. 299 participants with allergic rhinitis (seasonal or perennial) were selected. Skin prick test using twenty three common allergen extracts was performed on all patients.
RESULTS
The overall frequency of sensitization to any allergen was 85.6%. In outdoor allergens the most prevalent aeroallergen category was weeds (89%) followed by tree and grasses, and in indoor allergens, mites (43%) were the most prevalent aeroallergen. The mean and median numbers of positive test reactions among those with positive test responses were 11.5 and 13.0, respectively. 84% of patients were poly-sensitised and about 50% of them were sensitised to more than twelve different allergens.
CONCLUSION
The results of the study revealed that prevalence of the skin prick reactivity to weed pollens is significant in southwest Iran and multiple sensitizations were common.
背景
呼吸道过敏是世界上最重要的公共卫生问题。它们是由过敏原引起的，这些过敏原在呼吸道过敏疾病的发病机制中起重要作用。
方法
本研究旨在评估伊朗西南部阿瓦兹过敏患者对各种气传过敏原皮肤点刺试验阳性的患病率。选择了 299 名患有过敏性鼻炎（季节性或常年性）的患者。对所有患者进行了 23 种常见过敏原提取物的皮肤点刺试验。
结果
对任何过敏原的总致敏率为 85.6%。在室外过敏原中，最常见的气传过敏原类别是杂草（89%），其次是树木和草类，而在室内过敏原中，螨类（43%）是最常见的气传过敏原。对阳性测试反应者的平均和中位数阳性测试反应数分别为 11.5 和 13.0。84%的患者为多敏化，其中约 50%的患者对超过 12 种不同的过敏原过敏。
结论
该研究结果表明，在伊朗西南部，杂草花粉的皮肤点刺反应发生率显著，且多重致敏较为常见。
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