Bioengineering Research Laboratory, The Hand and Upper Limb Centre, St. Joseph's Health Care London, London, Ontario, Canada.
J Biomech. 2013 Jun 21;46(10):1767-71. doi: 10.1016/j.jbiomech.2013.04.001. Epub 2013 May 9.
It is important to study joint contact mechanics to better understand the processes which lead to cartilage degradation. The purpose of this study was to develop and validate a finite element (FE) model of a human elbow capable of predicting joint contact area and stress. A cylindrical constrained elbow joint loading apparatus was used to measure the cartilage compression and contact area for a single cadaveric specimen. A computer model of the same joint was created based on computed tomography images of the specimen, and the same loading was simulated using FE contact analysis. The model-predicted joint compression and contact area corresponded closely with experiment-measured results (differences of -4.9% and +9.6%). A sensitivity analysis showed that the model results were sensitive to cartilage and bone material properties, as well as the cartilage thickness distribution. The results of this study underline the importance of using accurate material properties and physiological cartilage thickness distributions when simulating cartilage contact mechanics.
研究关节接触力学对于更好地理解导致软骨退化的过程非常重要。本研究的目的是开发和验证一种能够预测关节接触面积和应力的人类肘部有限元(FE)模型。使用圆柱形约束肘部关节加载装置测量单个尸体标本的软骨压缩和接触面积。根据标本的计算机断层扫描图像创建了相同关节的计算机模型,并使用 FE 接触分析模拟相同的加载。模型预测的关节压缩和接触面积与实验测量结果非常吻合(差异分别为-4.9%和+9.6%)。敏感性分析表明,模型结果对软骨和骨材料特性以及软骨厚度分布敏感。本研究的结果强调了在模拟软骨接触力学时使用准确的材料特性和生理软骨厚度分布的重要性。