Martin-Luther-Universität Halle-Wittenberg, Organische Chemie, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany.
Bioorg Med Chem Lett. 2013 Jun 15;23(12):3542-6. doi: 10.1016/j.bmcl.2013.04.036. Epub 2013 Apr 23.
During the reaction of methyl 3β-acetoxy-glycyrrhetinate (1) with SeO2 significant amounts of a cytotoxic hitherto unprecedented triterpenoic selenophene 3 are formed. This compound stops cell proliferation and acts by apoptosis.
在甲基 3β-乙酰氧基甘草次酸（1）与 SeO2 的反应过程中，会形成大量具有细胞毒性的、前所未有的三萜硒吩 3。该化合物能阻止细胞增殖，并通过细胞凋亡发挥作用。
