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逐级减小有序纳米孔硅材料的孔径至埃精度。

Stepwise pore size reduction of ordered nanoporous silica materials at angstrom precision.

机构信息

ARC Centre of Excellence for Functional Nanomaterials and Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia.

出版信息

J Am Chem Soc. 2013 Jun 12;135(23):8444-7. doi: 10.1021/ja402463h. Epub 2013 May 15.

DOI:10.1021/ja402463h
PMID:23668366
Abstract

A facile vacuum-assisted vapor deposition process has been developed to control the pore size of ordered mesoporous silica materials in a stepwise manner with angstrom precision, providing an unprecedented paradigm for screening a designer hydrophobic drug nanocarrier with optimized pore diameter to maximize drug solubility.

摘要

一种简便的真空辅助蒸汽沉积工艺已被开发出来，能够以埃精度逐步控制有序介孔硅材料的孔径，为筛选具有优化孔径的疏水性药物纳米载体提供了前所未有的范例，以最大限度地提高药物溶解度。

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