Department of Ophthalmology V, Quinze-Vingts National Ophthalmology Hospital, Paris, France.
Am J Ophthalmol. 2013 Aug;156(2):319-325.e1. doi: 10.1016/j.ajo.2013.03.035. Epub 2013 May 10.
To evaluate the outcomes of epiretinal membrane (ERM) surgery in highly myopic eyes without traction maculopathy, and to compare them with those from non-highly myopic eyes.
Retrospective nested case-control study from a cohort of 509 consecutive patients (509 eyes) who underwent pars plana vitrectomy with ERM removal.
Thirty-two highly myopic eyes (with a refractive error of more than -6.00 diopters [D]), which underwent surgery for isolated ERM, were included in the study. For each case studied, we selected from the same cohort 2 age-matched controls who had ERM surgery (n = 64 non-highly myopic eyes). The best-corrected visual acuity (BCVA), the central macular thickness (CMT), and the surgical complications were analyzed.
The mean follow-up duration was 3.2 ± 1.5 years for the study cases and 3.4 ± 1.6 years for the control group (P = .608). At the final follow-up examination, the mean logMAR BCVA had improved significantly, from 0.56 to 0.26 (P < .001) for the case group and from 0.54 to 0.22 (P < .001) for the control group. At the final optical coherence tomography (OCT), the mean CMT had improved significantly, from 433 to 314 μm (P < .001) for the case group and from 428 to 303 μm (P < .001) for the control group. There was no significant difference between the 2 groups as regards visual or CMT improvement (P = .526 and P = .483, respectively). The incidence of surgical complications was not significant between the 2 groups.
The results of ERM surgery were not different in terms of anatomic and visual outcomes and surgical complication between highly myopic and non-highly myopic eyes.
评估无牵引性黄斑病变的高度近视眼行视网膜内界膜（ERM）手术的结果，并与非高度近视眼进行比较。
对 509 例（509 只眼）连续接受经睫状体平坦部玻璃体切除术联合 ERM 切除的患者队列进行回顾性巢式病例对照研究。
纳入 32 只高度近视眼（屈光度>-6.00 屈光度），这些眼仅因孤立性 ERM 而接受手术。对每只研究眼，我们从同一队列中选择 2 名年龄匹配的 ERM 手术患者作为对照（n=64 只非高度近视眼）。分析最佳矫正视力（BCVA）、中心黄斑厚度（CMT）和手术并发症。
研究病例的平均随访时间为 3.2±1.5 年，对照组为 3.4±1.6 年（P=0.608）。在最终随访检查时，研究病例组的平均 logMAR BCVA 显著提高，从 0.56 提高至 0.26（P<0.001），对照组从 0.54 提高至 0.22（P<0.001）。在最终光学相干断层扫描（OCT）时，研究病例组的平均 CMT 显著降低，从 433μm 降低至 314μm（P<0.001），对照组从 428μm 降低至 303μm（P<0.001）。两组间视力和 CMT 改善的差异无统计学意义（P=0.526 和 P=0.483）。两组间手术并发症的发生率无显著差异。
在解剖和视觉结果以及手术并发症方面，高度近视眼和非高度近视眼行 ERM 手术的结果无差异。
