de Smet P A, Stricker B H, Wilderink F, Wiersinga W M
Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, Geneesmiddel Informatie Centrum, Gravenhage.
Ned Tijdschr Geneeskd. 1990 May 26;134(21):1058-9.
A 50-year-old healthy woman started daily treatment with six iodine-containing kelp tablets (Kelpasan), containing 200 mg of kelp each, to lose weight; she took no other medication. Within two months she developed clinical and laboratory evidence of hyperthyroidism, which resolved spontaneously following discontinuation of the tablets. A causal relationship between the intake of the kelp preparation and the thyrotoxic episode could not be established beyond all possible doubt, but the clinical picture and clear temporal relationship strongly pointed in this direction.
一名50岁的健康女性开始每日服用6片含碘海带片(Kelpasan)以减肥,每片含200毫克海带;她未服用其他药物。两个月内,她出现了甲状腺功能亢进的临床和实验室证据,停用该片剂后甲状腺功能亢进症自发缓解。虽然不能完全确定海带制剂的摄入与甲状腺毒症发作之间存在因果关系,但临床表现和明确的时间关系强烈指向这一方向。