Deutsches Herzzentrum und I. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Thromb Res. 2013 Jun;131(6):474-80. doi: 10.1016/j.thromres.2013.04.017. Epub 2013 May 10.
The immunoglobulin superfamily member EMMPRIN (CD147) plays an important role in a number of organ systems, including the cardiovascular system. Here we review the contemporary understanding of EMMPRIN and EMMPRIN-associated sequelae in the course of atherosclerosis. A significant body of data documents the pivotal role of EMMPRIN in the complex processes of atherogenesis, atheroprogression, and acute atherosclerothrombosis, a role that goes beyond that of a mere marker of inflammation.
免疫球蛋白超家族成员 EMMPRIN（CD147）在许多器官系统中发挥重要作用，包括心血管系统。在这里，我们回顾了对 EMMPRIN 及其在动脉粥样硬化过程中相关后果的当代认识。大量数据表明，EMMPRIN 在动脉粥样硬化形成、动脉粥样硬化进展和急性动脉粥样硬化血栓形成等复杂过程中起着关键作用，其作用不仅仅是炎症的标志物。
