Clinic for Visceral and Transplantation Surgery, Department of Surgery, Faculty of Medicine, University Hospital of Geneva, University of Geneva, Rue Gabriel-Perret-Gentil, 4, 1211, Geneva 14, Switzerland,
Surg Endosc. 2013 Oct;27(10):3897-901. doi: 10.1007/s00464-013-3005-5. Epub 2013 May 14.
With the introduction of a new platform, robotic single-site cholecystectomy (RSSC) has been reported as feasible and safe for selected cases. In parallel, the development of real-time near-infrared fluorescent cholangiography using indocyanine green (ICG) has been seen as a help during the dissection, even if the data are still preliminary. The study purpose is to report our experience with ICG RSSC and compare the outcomes to standard RSSC.
From February 2011 to December 2011, 44 selected patients underwent RSSC for symptomatic cholelithiasis. Among them, 23 (52.3%) were included in an experimental protocol using the ICG, and the remainder (47.7%) underwent standard RSSC. There was no randomization. The endpoints were the perioperative outcomes. This is a prospective study, approved by our local Ethics Committee.
There were no differences in terms of patients' characteristics, except that there were more male patients in the ICG group (47.8 vs. 9.5%; p = 0.008). Regarding the surgical data, the overall operative time was shorter for the ICG group, especially for patients with a body mass index (BMI) ≤25 (-24 min) but without reaching statistical significance (p = 0.06). For BMI >25, no differences were observed. Otherwise, there were no differences in terms of conversion, complications, or length of stay between both groups.
A RSSC with a real-time near-infrared fluorescent cholangiography can be performed safely. In addition, for selected patients with a low BMI, ICG could shorten the operative time during RSSC. Larger studies are still required before drawing definitive conclusions.
随着新平台的引入,机器人单部位胆囊切除术(RSSC)已被报道在某些情况下是可行且安全的。同时,使用吲哚菁绿(ICG)进行实时近红外荧光胆管造影术的发展也被认为有助于手术解剖,尽管数据仍初步。本研究旨在报告我们使用 ICG 进行 RSSC 的经验,并将结果与标准 RSSC 进行比较。
从 2011 年 2 月至 2011 年 12 月,44 例有症状的胆石症患者接受 RSSC 治疗。其中,23 例(52.3%)纳入了使用 ICG 的实验方案,其余 47.7%则接受了标准 RSSC。没有进行随机化。研究终点为围手术期结果。这是一项经我们当地伦理委员会批准的前瞻性研究。
患者特征无差异,除了 ICG 组的男性患者更多(47.8% vs. 9.5%;p = 0.008)。就手术数据而言,ICG 组的总体手术时间更短,特别是 BMI≤25 的患者(-24 分钟),但无统计学意义(p = 0.06)。BMI>25 的患者则无差异。此外,两组之间在转换、并发症或住院时间方面均无差异。
实时近红外荧光胆管造影术的 RSSC 可以安全进行。此外,对于 BMI 较低的选定患者,ICG 可缩短 RSSC 期间的手术时间。仍需要更大规模的研究来得出明确的结论。