University of British Columbia, Vancouver, British Columbia, Canada; Laboratory Medicine, the Department of Clinical Pathology, and the Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Transfusion. 2014 Jan;54(1):66-73; quiz 65. doi: 10.1111/trf.12240. Epub 2013 May 14.
This report provides a comprehensive analysis of transfusion errors occurring at a large teaching hospital and aims to determine key errors that are threatening transfusion safety, despite implementation of safety measures.
Errors were prospectively identified from 2005 to 2010. Error data were coded on a secure online database called the Transfusion Error Surveillance System. Errors were defined as any deviation from established standard operating procedures. Errors were identified by clinical and laboratory staff. Denominator data for volume of activity were used to calculate rates.
A total of 15,134 errors were reported with a median number of 215 errors per month (range, 85-334). Overall, 9083 (60%) errors occurred on the transfusion service and 6051 (40%) on the clinical services. In total, 23 errors resulted in patient harm: 21 of these errors occurred on the clinical services and two in the transfusion service. Of the 23 harm events, 21 involved inappropriate use of blood. Errors with no harm were 657 times more common than events that caused harm. The most common high-severity clinical errors were sample labeling (37.5%) and inappropriate ordering of blood (28.8%). The most common high-severity error in the transfusion service was sample accepted despite not meeting acceptance criteria (18.3%). The cost of product and component loss due to errors was $593,337.
Errors occurred at every point in the transfusion process, with the greatest potential risk of patient harm resulting from inappropriate ordering of blood products and errors in sample labeling.
本报告全面分析了一家大型教学医院发生的输血错误,并旨在确定尽管采取了安全措施,但仍存在威胁输血安全的关键错误。
从 2005 年到 2010 年,前瞻性地识别错误。将错误数据编码到名为“输血错误监测系统”的安全在线数据库中。将错误定义为任何偏离既定标准操作程序的行为。由临床和实验室工作人员识别错误。使用活动量的分母数据计算发生率。
共报告了 15134 次错误,每月中位数为 215 次(范围 85-334)。总体而言,9083 次(60%)错误发生在输血服务部门,6051 次(40%)发生在临床服务部门。共有 23 次错误导致患者受到伤害:其中 21 次发生在临床服务部门,2 次发生在输血服务部门。在这 23 次伤害事件中,有 21 次涉及血液的不当使用。无伤害的错误比导致伤害的事件常见 657 倍。最常见的高严重性临床错误是样本标记(37.5%)和血液不当订购(28.8%)。输血服务中最常见的高严重性错误是样本接受,尽管不符合接受标准(18.3%)。由于错误导致的产品和组件损失的成本为 593337 美元。
错误发生在输血过程的每个环节,最有可能导致患者受到伤害的风险来自血液制品的不当订购和样本标记错误。