Khan Sikandar, Ur Rahman Asad, Castillo Michael, Riaz Amir, Miret Rafael, Bejarano Pablo, Castro-Pavia Fernando
Department of Internal Medicine, Cleveland Clinic Florida, Weston, FL.
Department of Gastroenterology and Hepatology, Cleveland Clinic Florida, Weston, FL.
ACG Case Rep J. 2021 Jan 13;8(1):e00529. doi: 10.14309/crj.0000000000000529. eCollection 2021 Jan.
Squamous cell carcinoma (SCC) of the colon, both primary and metastatic, are extremely rare malignancies. We present a case of a 60-year-old man with metastatic SCC of the tongue status after radiation and chemotherapy who presented with fatigue and melena. Colonoscopy revealed a 5 cm mass in the transverse colon. Pathology established the diagnosis of poorly differentiated SCC with p16 immunostaining, similar to biopsies from his initially diagnosed lingual cancer. To the best of our knowledge, there are no previously reported cases of primary SCC of the tongue metastasizing to the colon.
结肠鳞状细胞癌（SCC），无论是原发性还是转移性，都是极其罕见的恶性肿瘤。我们报告一例60岁男性病例，该患者患有经放疗和化疗后的舌转移性SCC，出现疲劳和黑便症状。结肠镜检查发现横结肠有一个5厘米的肿块。病理检查通过p16免疫染色确诊为低分化SCC，与最初诊断的舌癌活检结果相似。据我们所知，此前尚无舌原发性SCC转移至结肠的病例报道。
