de Palma Luigi, Candelari Roberto, Antico Ettore, Politano Rocco, Luniew Eugenio, Giordanengo Maurizio, Di Giansante Silvio, Marinelli Mario, Paci Enrico
Clinic Orthopaedic, Marche Polytechnic University, Ancona Hospital, Via Conca 71, 60100 Ancona, Italy.
Orthopedics. 2013 May;36(5):e581-7. doi: 10.3928/01477447-20130426-19.
Osteoid osteoma is a benign bone tumor with a male predominance occurring mainly in children and young adults. The most common symptom is intermittent pain that worsens at night and is at least partially relieved by nonsteroidal anti-inflammatory drugs. The purpose of this study was to assess the long-term effectiveness of computed tomography-guided percutaneous radiofrequency thermoablation in patients with a minimum follow-up of 2 years. Twenty patients with osteoid osteoma (15 men and 5 women) with a mean age of 20.7 years (range, 4-61 years; 12 patients aged 20 years or younger) underwent computed tomography-guided percutaneous radiofrequency thermoablation. Lesion sites were the femur (n=9), tibia (n=7), pelvis (n=1), talus (n=1), cuneiform bone (n=1), and humerus (n=1). Mean follow-up was 44 months (range, 3-106 months). Pain relief was significant in 95% of patients; it disappeared within 24 hours in 14 patients, within 3 days in 4, and within 7 days in 1. The patient with persistent symptoms underwent another percutaneous radiofrequency thermoablation procedure that was successful. The difference between pre- and postoperative pain was significant (P ≤ .01). No recurrences occurred. Computed tomography-guided percutaneous radiofrequency thermoablation is a safe, minimally invasive, and economical procedure with high technical and clinical success rates, and it effectively and durably enhances quality of life.
骨样骨瘤是一种良性骨肿瘤,男性居多,主要发生于儿童和青年。最常见的症状是间歇性疼痛,夜间加重,非甾体类抗炎药可至少部分缓解疼痛。本研究的目的是评估计算机断层扫描引导下经皮射频热消融术在至少随访2年的患者中的长期疗效。20例骨样骨瘤患者(15例男性和5例女性),平均年龄20.7岁(范围4 - 61岁;12例年龄20岁及以下)接受了计算机断层扫描引导下经皮射频热消融术。病变部位为股骨(n = 9)、胫骨(n = 7)、骨盆(n = 1)、距骨(n = 1)、楔骨(n = 1)和肱骨(n = 1)。平均随访44个月(范围3 - 106个月)。95%的患者疼痛明显缓解;14例患者疼痛在24小时内消失,4例在3天内消失,1例在7天内消失。有持续症状的患者接受了另一次成功的经皮射频热消融术。术前和术后疼痛差异有统计学意义(P≤0.01)。无复发发生。计算机断层扫描引导下经皮射频热消融术是一种安全、微创且经济的手术,技术和临床成功率高,能有效且持久地提高生活质量。