Suppr超能文献

心脏手术后在重症监护病房长时间停留:早期结果和晚期生存。

Very prolonged stay in the intensive care unit after cardiac operations: early results and late survival.

机构信息

Department of Cardiothoracic Surgery, Shaare Zedek Medical Center affiliated with the Hebrew University of Jerusalem, Jerusalem, Israel.

出版信息

Ann Thorac Surg. 2013 Jul;96(1):15-21; discussion 21-2. doi: 10.1016/j.athoracsur.2013.01.103. Epub 2013 May 11.

Abstract

BACKGROUND

Prolonged intensive care unit (ICU) stay is a surrogate for advanced morbidity or perioperative complications, and resource utilization may become an issue. It is our policy to continue full life support in the ICU, even for patients with a seemingly grim outlook. We examined the effect of duration of ICU stay on early outcomes and late survival.

METHODS

Between 1993 and 2011, 6,385 patients were admitted to the ICU after cardiac surgery. Patients were grouped according to length of stay in the ICU: group 1, 2 days or less (n = 4,631; 73%); group 2, 3 to 14 days (n = 1,423; 22%); group 3, more than 14 days (n = 331; 5%). Length of stay in ICU for group 3 patients was 38 ± 24 days (range, 15 to 160; median 31). Clinical profile and outcomes were compared between groups.

RESULTS

Patients requiring prolonged ICU stay were older, underwent more complex surgery, had greater comorbidity, and a higher predicted operative mortality (p < 0.0001). They had a higher incidence of adverse events and increased mortality (p < 0.0001). Of the 331 group 3 patients, 60% were discharged: survival of these patients at 1, 3, and 5 years was 78%, 65%, and 52%, respectively. Operative mortality as well as late survival of discharged patients was proportional to duration of ICU stay.

CONCLUSIONS

Current technology enables keeping sick patients alive for extended periods of time. Nearly two thirds of patients requiring prolonged ICU leave hospital, and of these, 50% attain 5-year survival. These data support offering full and continued support even for patients requiring very prolonged ICU stay.

摘要

背景

长时间的重症监护病房(ICU)住院是严重发病率或围手术期并发症的替代指标,资源利用可能成为一个问题。我们的政策是继续在 ICU 提供全面的生命支持,即使是对预后极差的患者也是如此。我们研究了 ICU 住院时间对早期结果和晚期生存的影响。

方法

1993 年至 2011 年间,6385 例心脏手术后患者入住 ICU。根据 ICU 住院时间将患者分为以下几组:第 1 组,住院时间 2 天或更短(n=4631;73%);第 2 组,住院时间 3 至 14 天(n=1423;22%);第 3 组,住院时间超过 14 天(n=331;5%)。第 3 组患者的 ICU 住院时间为 38±24 天(范围 15 至 160 天;中位数 31 天)。比较各组间的临床特征和结局。

结果

需要长时间 ICU 住院的患者年龄较大,接受了更复杂的手术,合并症更多,预测手术死亡率更高(p<0.0001)。他们不良事件发生率更高,死亡率增加(p<0.0001)。第 3 组 331 例患者中,有 60%出院:这些患者出院后 1、3 和 5 年的生存率分别为 78%、65%和 52%。手术死亡率和出院患者的晚期生存率与 ICU 住院时间成正比。

结论

目前的技术使患者能够在延长的时间内维持生命。近三分之二需要长时间 ICU 治疗的患者出院,其中 50%的患者获得了 5 年生存率。这些数据支持为需要长时间 ICU 治疗的患者提供全面和持续的支持。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验