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Chocolate in history: food, medicine, medi-food.巧克力的历史:食物、药物、介于食物和药物之间的物质。
Nutrients. 2013 May 14;5(5):1573-84. doi: 10.3390/nu5051573.
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Sin and pleasure: the history of chocolate in medicine.罪恶与愉悦:巧克力在医学中的历史。
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Food of the gods: cure for humanity? A cultural history of the medicinal and ritual use of chocolate.神之食物:能治愈人类吗?巧克力药用与仪式用途的文化史。
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[Cacao in traditional Central American medicine].[传统中美洲医学中的可可]
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Pharos Alpha Omega Alpha Honor Med Soc. 2001 Spring;64(2):22-6.
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Extreme chocolate: the quest for the perfect bean.极致巧克力:对完美可可豆的探寻。
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Cell surface ATP synthase-released H and ATP play key roles in cocoa butter intake-mediated regulation of gut immunity through releases of cytokines in rat.细胞表面 ATP 合酶释放的 H 和 ATP 通过在大鼠中释放细胞因子在可可脂摄入介导的肠道免疫调节中发挥关键作用。
Pflugers Arch. 2023 Aug;475(8):945-960. doi: 10.1007/s00424-023-02822-y. Epub 2023 Jun 1.
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Chocolate, "Food of the Gods": History, Science, and Human Health.巧克力,“众神的食物”:历史、科学与人类健康。
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Dark Chocolate: Opportunity for an Alliance between Medical Science and the Food Industry?黑巧克力:医学与食品行业结盟的契机?
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Effect of Procyanidin-rich Extract from Natural Cocoa Powder on Cellular Viability, Cell Cycle Progression, and Chemoresistance in Human Epithelial Ovarian Carcinoma Cell Lines.天然可可粉中富含原花青素的提取物对人上皮性卵巢癌细胞系细胞活力、细胞周期进程及化疗耐药性的影响
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Plants Consumption and Liver Health.植物性食物的摄入与肝脏健康。
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The acute and sub-chronic effects of cocoa flavanols on mood, cognitive and cardiovascular health in young healthy adults: a randomized, controlled trial.可可黄烷醇对年轻健康成年人情绪、认知和心血管健康的急性和亚慢性影响:一项随机对照试验。
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本文引用的文献

1
The physiology of extremes: Ancel Keys and the International High Altitude Expedition of 1935.极端环境生理学:安塞尔·基斯与1935年国际高原探险队
Bull Hist Med. 2012 Winter;86(4):627-60. doi: 10.1353/bhm.2012.0079.
2
Chocolate consumption, cognitive function, and Nobel laureates.巧克力消费、认知功能与诺贝尔奖获得者
N Engl J Med. 2012 Oct 18;367(16):1562-4. doi: 10.1056/NEJMon1211064. Epub 2012 Oct 10.
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Centuries of seeking chocolate's medicinal benefits.
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Chocolate in health and disease.
Maturitas. 2010 Nov;67(3):195-6. doi: 10.1016/j.maturitas.2010.06.010. Epub 2010 Jul 6.
5
Chocolate and medicine: dangerous liaisons?巧克力与药物:危险的结合?
Nutrition. 2009 Nov-Dec;25(11-12):1100-3. doi: 10.1016/j.nut.2009.08.002.
6
Chemical and archaeological evidence for the earliest cacao beverages.最早可可饮料的化学及考古学证据。
Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18937-40. doi: 10.1073/pnas.0708815104. Epub 2007 Nov 16.
7
Food of the gods: cure for humanity? A cultural history of the medicinal and ritual use of chocolate.神之食物:能治愈人类吗?巧克力药用与仪式用途的文化史。
J Nutr. 2000 Aug;130(8S Suppl):2057S-72S. doi: 10.1093/jn/130.8.2057S.

巧克力的历史:食物、药物、介于食物和药物之间的物质。

Chocolate in history: food, medicine, medi-food.

机构信息

Department of Experimental and Clinical Medicine, Section of Health Services, Largo Brambilla 3, 50134 Florence, Italy.

出版信息

Nutrients. 2013 May 14;5(5):1573-84. doi: 10.3390/nu5051573.

DOI:10.3390/nu5051573
PMID:23673608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3708337/
Abstract

Throughout history, chocolate has been used to treat a wide variety of ailments, and in recent years, multiple studies have found that chocolate can have positive health effects, providing evidence to a centuries-long established use; this acknowledgement, however, did not have a straight course, having been involved in religious, medical and cultural controversies. Christian Europe, in fact, feared the exhilarating effects of new drinks, such as chocolate, coffee and tea. Therefore, these beverages would have been banished, had not doctors and scientists explained that they were good for the body. The scientific debate, which reached its peak in Florence in the 18th century, regarded the therapeutic effectiveness of the various chocolate components: it was necessary to know their properties first, in order to prepare the best cacao concoction for every patient. When Dietetics separated from Medicine, however, chocolate acquired the role of vehicle for easing the administration of bitter medicines, being associated to different health problems. The recent rediscovery of the beneficial use of cacao and chocolate focuses upon its value as supplemental nutrition. Building a bridge to the past may be helpful to detect the areas where the potential health benefits of chocolate are likely to be further explored.

摘要

纵观历史,巧克力被用于治疗各种疾病,近年来,多项研究发现巧克力对健康有积极影响,为其几个世纪以来的应用提供了证据;然而,这种认可并非一帆风顺,它涉及宗教、医学和文化等方面的争议。事实上,基督教欧洲对巧克力、咖啡和茶等新饮料的兴奋作用感到恐惧。因此,如果没有医生和科学家解释说这些饮料对身体有益,它们可能就会被禁止。这场科学争论在 18 世纪的佛罗伦萨达到了顶峰,涉及到各种巧克力成分的治疗效果:首先必须了解它们的特性,才能为每个病人准备最好的可可混合物。然而,当营养学从医学中分离出来后,巧克力就成为了缓解苦味药物的给药途径,与不同的健康问题相关联。最近对可可和巧克力有益用途的重新发现,关注的是其作为补充营养的价值。回顾过去可能有助于发现巧克力的潜在健康益处可能进一步探索的领域。