Abdel Baieth H E
Department of Physics, Faculty of Science, King Faisal University, Saudi Abrabia Kingdom.
Int J Biomed Sci. 2009 Sep;5(3):229-36.
The aim of the present work is to study if the GBE 761 (Ginkgo biloba leaves extract) which is beneficial in arterial disease owing to its vasodilator and blood flow acts against the hazards of exposure to electromagnetic field. Here, the GBE was used in two ways either as a protector or for treating the hazards due to exposure to electromagnetic field (EMF). For this purpose, albino rats were grouped into six groups and blood samples were collected from eye vein of the animals from all groups at the end of the experiment. This study concentrates on the cellular membrane and function of the RBCs and focuses on the rheological and physical measurements for blood and hemoglobin molecule because the RBCs membranes play an essential role in the blood flow rate. The changes in its biophysical properties of RBCs membrane will affect its capability for carrying on its metabolic functions. Furthermore, the molecular diameter of hemoglobin, its relaxation time and conductivity were calculated from the dielectric relaxation data. The results indicate that the administration of GBE led to the decrease of RBCs membrane elasticity will lead to the increase of the blood viscosity. Results suggest that GBE may be not of clinical value as anti-oxidant drug for such diseases occurred due to to EMF exposure for long time. It may be conclude that through treatment with those extract some physical measurements like "viscosity of blood, Osmotic fragility to measure the hemolysis rat of RBCs, the radius and the conductivity of hemoglobin molecule" should be considered during the time of treatment. Overall, these leaves (GBE) need more study and there is a recommendation to put the physical parameters parallel to the clinical study.
本研究的目的是探讨具有血管舒张和促进血流作用、对动脉疾病有益的银杏叶提取物GBE 761是否能对抗暴露于电磁场的危害。在此，GBE以两种方式使用，要么作为保护剂，要么用于治疗因暴露于电磁场（EMF）而产生的危害。为此，将白化大鼠分为六组，并在实验结束时从所有组的动物眼静脉采集血样。本研究集中于红细胞的细胞膜和功能，并着重于血液和血红蛋白分子的流变学和物理测量，因为红细胞膜在血流速率中起着至关重要的作用。红细胞膜生物物理特性的变化将影响其进行代谢功能的能力。此外，根据介电弛豫数据计算血红蛋白的分子直径、弛豫时间和电导率。结果表明，给予GBE导致红细胞膜弹性降低，进而导致血液粘度增加。结果表明，对于因长期暴露于EMF而发生的此类疾病，GBE作为抗氧化药物可能没有临床价值。可以得出结论，在治疗期间，通过使用这些提取物，应考虑一些物理测量指标，如“血液粘度、测量红细胞溶血率的渗透脆性、血红蛋白分子的半径和电导率”。总体而言，这些叶子（GBE）需要更多的研究，建议将物理参数与临床研究并行。
