Biology Department, Faculty of Science, Selcuk University, Konya, Turkey.
Pharm Biol. 2013 Jun;51(6):707-11. doi: 10.3109/13880209.2013.764327.
Terfezia boudieri Chatin (Pezizaceae), Agaricus brunnescens Peck (Agaricaceae) and Lactarius vellereus (Fr.) Fr. (Russulaceae) are well-known species in Turkey, and are used both for food and traditional medicine.
The powdered fruit bodies of T. boudieri, A. brunnescens and L. vellereus were used to evaluate the antimicrobial activities.
Chloroform, acetone and methanol extracts of T. boudieri, A. brunnescens and L. vellereus were tested for their antimicrobial activities against four Gram-positive bacteria, five Gram-negative bacteria and yeast using a micro-dilution method.
The strongest minimum inhibitory concentration (MIC) value observed against the test microorganisms was with the chloroform extract of T. boudieri (MIC 2.4 µg/mL) against Streptococcus pyogenes. Maximum antimicrobial effects were observed with the acetone extracts of T. boudieri and L. vellereus (MIC 4.8 µg/mL) against Bacillus subtilis. The strongest antifungal activity was observed with the acetone extracts of T. boudieri (MIC 2.4 µg/mL) and A. brunnescens (MIC 19.5 µg/mL) against Candida albicans. The strongest MIC values for all fungal extracts were observed between 78 and 2.4 µg/mL.
Present results demonstrated that these three mushroom species have excellent antimicrobial and antifungal activities, and thus have great potential as a source for natural health products.
土耳其特菲芝（Pezizaceae）、红绒盖牛肝菌（Agaricaceae）和乳菇（Russulaceae）是众所周知的物种，既用于食品又用于传统医学。
特菲芝、红绒盖牛肝菌和乳菇的粉状子实体用于评估其抗菌活性。
采用微量稀释法，测试特菲芝、红绒盖牛肝菌和乳菇的氯仿、丙酮和甲醇提取物对四种革兰氏阳性菌、五种革兰氏阴性菌和酵母的抗菌活性。
对测试微生物观察到的最强最小抑菌浓度（MIC）值是特菲芝的氯仿提取物（MIC 2.4μg/mL）对化脓性链球菌。特菲芝和乳菇的丙酮提取物对枯草芽孢杆菌表现出最大的抗菌作用（MIC 4.8μg/mL）。特菲芝和红绒盖牛肝菌的丙酮提取物对白色念珠菌表现出最强的抗真菌活性（MIC 2.4μg/mL）和红绒盖牛肝菌（MIC 19.5μg/mL）。所有真菌提取物的最强 MIC 值在 78 和 2.4μg/mL 之间。
目前的结果表明，这三种蘑菇具有极好的抗菌和抗真菌活性，因此具有作为天然保健品来源的巨大潜力。
