Orii Makoto, Kubo Takashi, Tanaka Atsushi, Kitabata Hironori, Ino Yasushi, Shiono Yasutsugu, Shimamura Kunihiro, Aoki Hiroshi, Ohta Shingo, Ozaki Yuichi, Ishibashi Kohei, Yamano Takashi, Tanimoto Takashi, Yamaguchi Tomoyuki, Hirata Kumiko, Imanishi Toshio, Akasaka Takashi
Department of Cardiovascular Medicine, Wakayama Medical University, Kimiidera, Wakayama, Japan.
Int Heart J. 2013;54(2):64-7. doi: 10.1536/ihj.54.64.
Frequency-domain optical coherence tomography (FD-OCT) is a novel technology which provides high-resolution cross-sectional images of coronary arteries. The aim of this study was to evaluate the inter-scan reproducibility of geometric FD-OCT measurements in the clinical setting. We examined 20 coronary lesions using FD-OCT. Following the FD-OCT image acquisition (1st pullback), and after the disengagement and re-engagement of the guiding catheter, an additional acquisition (2nd pullback) was performed using a new FD-OCT catheter. There was excellent correlation for minimum lumen area (r = 0.99, P < 0.001), lesion length (r = 0.99, P < 0.001) and lumen volume (r = 0.99, P < 0.001) between the 1st pullback and the 2nd pullback. The Bland-Altman test demonstrated good agreement between the 1st pullback and the 2nd pullback: the mean difference for minimum lumen area, lesion length, and lumen volume was 0.05 mm(2), 0.03 mm, and 0.70 mm(3), respectively; and the lower and upper limit of agreement for minimum lumen area, lesion length, and lumen volume was -0.58 and 0.48, -0.36 and 0.42, and -13.4 and 12.1, respectively. FD-OCT showed an excellent inter-scan reproducibility for the geometric coronary artery measurements. Our findings emphasize the value of FD-OCT as a tool for clinical longitudinal studies of coronary artery disease.
频域光学相干断层扫描（FD - OCT）是一项能够提供冠状动脉高分辨率横截面图像的新技术。本研究的目的是评估在临床环境中FD - OCT几何测量的扫描间可重复性。我们使用FD - OCT检查了20处冠状动脉病变。在进行FD - OCT图像采集（第一次回撤）后，以及在撤出和重新插入引导导管后，使用新的FD - OCT导管进行了额外的采集（第二次回撤）。第一次回撤和第二次回撤之间，最小管腔面积（r = 0.99，P < 0.001）、病变长度（r = 0.99，P < 0.001）和管腔容积（r = 0.99，P < 0.001）具有极好的相关性。Bland - Altman检验表明第一次回撤和第二次回撤之间具有良好的一致性：最小管腔面积、病变长度和管腔容积的平均差异分别为0.05 mm²、0.03 mm和0.70 mm³；最小管腔面积、病变长度和管腔容积的一致性下限和上限分别为-0.58和0.48、-0.36和0.42以及-13.4和12.1。FD - OCT在冠状动脉几何测量方面显示出极好的扫描间可重复性。我们的研究结果强调了FD - OCT作为冠状动脉疾病临床纵向研究工具的价值。
