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[自身免疫性疾病中IgA的选择性缺乏]

[Selective deficiency of IgA in autoimmune diseases].

作者信息

Calabozo Raluy M, Gamir Gamir M L, Medina Luezas J, Díaz-Miguel Pérez C, Alonso Ruiz A

机构信息

Hospital Ramón y Cajal, Servicio de Reumatología, Madrid.

出版信息

Rev Clin Esp. 1990 Mar;186(4):163-5.

PMID:2367718
Abstract

A selective IgA deficiency (SD IgA) appears in a 0.15% of the population, being more frequent in autoimmune diseases. We present here eight patients presenting this association who were diagnosed at the Rheumatology Department during a period of eight years. Five patients suffered Juvenile Chronic Arthritis (JCA), two patients Rheumatoid Arthritis (RA) and one Systemic Lupus Erythematous (SLE). There were to cases of familiar deficiency. There was not a relationship between SD IgA and treatments used. There is an important association between SD IgA and JCA (4.27% prevalence). In the other two conditions, however, the association could be casual.

摘要

选择性IgA缺乏症(SD IgA)在0.15%的人群中出现,在自身免疫性疾病中更为常见。我们在此介绍八名在八年期间于风湿病科被诊断出患有这种关联疾病的患者。五名患者患有幼年慢性关节炎(JCA),两名患者患有类风湿性关节炎(RA),一名患者患有系统性红斑狼疮(SLE)。有两例家族性缺乏症。SD IgA与所使用的治疗方法之间没有关联。SD IgA与JCA之间存在重要关联(患病率为4.27%)。然而,在其他两种疾病中,这种关联可能是偶然的。

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