Cesaretti G, Calisti L, Giannessi N, Petrillo G, Fusaro C, Saggese G
Minerva Pediatr. 1989 May;41(5):267-71.
Three children with selective deficiency of serum IgA associated with oligoarticular juvenile rheumatoid arthritis (JRA) are presented. Before the appearance of JRA, all 3 children had shown frequently some respiratory infections. Indeed IgA deficiency may be asymptomatic or may cause a higher frequency of respiratory, gastrointestinal, allergic or autoimmune diseases, among which, JRA is one of the most important conditions.
本文报告了3例血清IgA选择性缺乏并伴有少关节型幼年类风湿关节炎(JRA)的患儿。在JRA出现之前,所有3例患儿均频繁出现一些呼吸道感染。事实上,IgA缺乏可能无症状,也可能导致呼吸道、胃肠道、过敏性或自身免疫性疾病的发病率升高,其中JRA是最重要的病症之一。