Kuboi Toru, Kusaka Takashi, Okazaki Kaoru, Kaku Uiko, Kakinuma Ryota, Kondo Masatoshi, Nishida Akira
Department of Neonatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Pediatr Int. 2013 Apr;55(2):e23-4. doi: 10.1111/j.1442-200X.2012.03730.x.
Hypoxic-ischemic encephalopathy in neonates causes irreversible damage to tissue and organs and results in multiple organ failure and poor outcome. Therapeutic hypothermia is the most effective therapy in neonates with hypoxic-ischemic encephalopathy. We report here a case of subcutaneous fat necrosis (SCFN) after therapeutic hypothermia by selective head cooling. Selective head cooling was provided for 72 h after birth. SCFN developed on the patient's cheeks and back at the age of 21 days. Thus, SCFN may be caused by selective head cooling, similarly to whole-body cooling.
新生儿缺氧缺血性脑病会对组织和器官造成不可逆损伤，导致多器官功能衰竭及预后不良。治疗性低温是新生儿缺氧缺血性脑病最有效的治疗方法。我们在此报告一例通过选择性头部降温进行治疗性低温后发生皮下脂肪坏死（SCFN）的病例。出生后进行了72小时的选择性头部降温。患儿在21日龄时脸颊和背部出现了SCFN。因此，与全身降温类似，SCFN可能是由选择性头部降温引起的。
