Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina.
Phys Rev Lett. 2013 Apr 26;110(17):178101. doi: 10.1103/PhysRevLett.110.178101. Epub 2013 Apr 22.
The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatiotemporal patterns of brain activity emerge from the empirically derived network of human brain neuroanatomical connections. The results show that critical dynamics unfolding on the structural connectivity of the human brain allow the recovery of many key experimental findings obtained from functional magnetic resonance imaging, such as divergence of the correlation length, the anomalous scaling of correlation fluctuations, and the emergence of large-scale resting state networks.
大脑结构与功能之间的关系是神经科学中的一个突出的开放性问题。我们通过研究从人类大脑神经解剖连接的经验得出的网络中出现的现实时空模式的动力学状态来解决这个问题。研究结果表明，在人类大脑的结构连接上展开的临界动力学允许从功能磁共振成像中恢复许多关键的实验结果，例如相关长度的发散、相关涨落的异常标度以及大尺度静息状态网络的出现。
