Instituto Valenciano de Investigaciones Agrarias (IVIA), Moncada, 46113, Valencia, Spain.
Arch Virol. 2013 Nov;158(11):2405-8. doi: 10.1007/s00705-013-1732-5. Epub 2013 May 17.
Lamium mild mosaic virus (LMMV) is the only one of the five members of the genus Fabavirus for which there are no nucleotide sequence data. In this study, the complete genome sequence of LMMV was determined and compared with the available complete genome sequences of other members of the genus Fabavirus. The genome was the largest of the genus but maintained the typical organization, with RNA 1 of 6080 nucleotides (nt), RNA 2 of 4065 nt, and an unusually long 3' untranslated region in RNA 2 of 603 nt. Phylogenetic analysis of the amino acid sequences of the protease-polymerase (Pro-Pol) region and the two coat proteins confirmed that LMMV belongs to a distinct species within the genus Fabavirus.
菜豆黄花叶病毒(LMMV)是五个菜豆花叶病毒属成员中唯一没有核苷酸序列数据的成员。在这项研究中,确定了 LMMV 的完整基因组序列,并与该属其他成员的可用完整基因组序列进行了比较。该基因组是该属中最大的,但保持了典型的组织,其中 RNA1 为 6080 个核苷酸(nt),RNA2 为 4065nt,RNA2 的 3'非翻译区异常长,为 603nt。蛋白酶-聚合酶(Pro-Pol)区和两个外壳蛋白的氨基酸序列的系统发育分析证实,LMMV 属于菜豆花叶病毒属中的一个独特种。