Di Marco A, Rizzotti A, Grandinetti A, Campostrini F, Palazzi M, Garusi G
Department of Radiation Oncology, Major Hospital of Verona, Italy.
Tumori. 1990 Jun 30;76(3):244-9. doi: 10.1177/030089169007600307.
A retrospective analysis of 183 consecutive patients with tonsillar carcinoma observed from 1970 through 1984 and treated by external radiotherapy was carried out. The data were analyzed retrospectively to determine the factors affecting prognosis. Tumor size (T) and lymph node involvement (N) were found to be predominant prognostic factors. The difference in 5 year survival rate between T2 and T3 tumors was significant, and that between N1 and N3 was highly significant, whereas difference in survival could be found between N0 and N1 groups. The primary tumor was controlled by radiotherapy alone in 90% of cases of T1 lesions, 58% of T2, 37% of T3 and 11% of T4, and lymph node metastases was controlled in 70% of N1 cases, 0 of N2 and 15.5% of N3. Twenty-three patients underwent salvage surgery after radiotherapy had failed and the actuarial 5 year survival rate was 75% for stage I, 40% for stage II, 30% for stage III and 13% for stage IV.
对1970年至1984年间连续观察到的183例扁桃体癌患者进行回顾性分析，这些患者均接受了外照射放疗。对数据进行回顾性分析以确定影响预后的因素。发现肿瘤大小（T）和淋巴结受累情况（N）是主要的预后因素。T2和T3肿瘤之间的5年生存率差异显著，N1和N3之间的差异高度显著，而N0和N1组之间也存在生存率差异。T1病变的90%、T2的58%、T3的37%和T4的11%的原发性肿瘤仅通过放疗得到控制，N1病例的70%、N2的0%和N3的15.5%的淋巴结转移得到控制。23例患者在放疗失败后接受了挽救性手术，I期的精算5年生存率为75%，II期为40%，III期为30%，IV期为13%。
