Stanevskaia T Iu, Grishkova L I
Urol Nefrol (Mosk). 1990 Mar-Apr(2):20-3.
Proteinuria, hematuria and leukocyturia in chronic alcoholics were mostly pronounced in abstinence, particularly in those with a long-term alcoholism. In proportion to alcohol d s-intoxication treatment, their urinalyses normalized. Being hospitalized in a sober state the patients had insignificantly elevated or practically normal urinalyses. Disulfiramum tests performed both in abstinence or sobriety demonstrated pronounced abnormalities in urinalyses. In the course of disulfuramum treatment in the absence of alcohol tests urinalyses normalized completely. Urinalysis follow-up demonstrated the appearance of renal failure due to hemodynamic disorders that ran the pattern of renal sensitization due to the effect of acetaldehyde production in alcohol tests.
慢性酒精中毒患者的蛋白尿、血尿和白细胞尿在戒酒时最为明显，尤其是那些长期酗酒者。随着酒精戒断治疗，他们的尿液分析结果恢复正常。患者在清醒状态下住院时，尿液分析结果仅有轻微升高或基本正常。在戒酒或清醒状态下进行的双硫仑试验显示尿液分析有明显异常。在双硫仑治疗过程中，在不进行酒精测试的情况下，尿液分析完全恢复正常。尿液分析随访显示，由于血液动力学紊乱出现了肾衰竭，其模式为酒精测试中乙醛产生的作用导致的肾致敏。
