Gobin Maya, Verlander Neville, Maurici Carla, Bone Angie, Nardone Anthony
Field Epidemiology Service, Public Health England, Bristol, UK.
BMC Public Health. 2013 May 17;13:484. doi: 10.1186/1471-2458-13-484.
A national multimedia campaign was launched in January 2010, to increase the proportion of young people tested for chlamydia. This study aimed to evaluate the impact of the campaign on the coverage and positivity within the National Chlamydia Screening Programme (NSCP) in England.
An interrupted time series of anonymised NCSP testing reports for England for a 27 month period (1st April 2008 to 30th June 2010) was analysed. Reports were assigned to a pre-campaign, campaign and post campaign phase according to the test date. Exclusion criteria included tests for clinical reasons, contacts of known cases, and tests returned from prisons or military services.Negative binomial and logistic regression modelling was used to provide an estimate for the change in coverage and positivity, during, and after the campaign and estimates were adjusted for secular and cyclical trends.
Adjusting for cyclical and secular trends, there was no change in the overall testing coverage either during (RR: 0.91; 95% CI: 0.72-1.14) or after (RR: 0.88; 95%CI: 0.69-1.11) the campaign. The coverage varied amongst different socio-demographic groups, testing of men increased during the campaign phase while testing of people of black and other ethnic groups fell in this phase. The positivity rate was increased during the campaign (OR: 1.18; 95% CI 1.13-1.23) and further increased in the post-campaign phase (OR: 1.40; 95% CI 1.30-1.51). The proportion of chlamydia infections detected increased for all socio-demographic and self-reported sexual behaviour groups both during and after the campaign.
The uptake of chlamydia testing rose during the campaign; however, this apparent increase was not maintained once overall trends in testing were taken into account. Nonetheless, once secular and cyclical trends were controlled for, the campaign was associated with an increased positivity linked to increased testing of high risk individuals groups in the target population who were previously less likely to come forward for testing. However, our study indicated that there may have been a disparity in the impact of the campaign on different population groups. The content and delivery of ongoing and future information campaigns aimed at increasing chlamydia screening should be carefully developed so that they are relevant to all sections of the target population.
2010年1月发起了一项全国性多媒体宣传活动,以提高接受衣原体检测的年轻人比例。本研究旨在评估该活动对英格兰国家衣原体筛查计划(NSCP)的覆盖率和阳性率的影响。
分析了27个月期间(2008年4月1日至2010年6月30日)英格兰匿名的NSCP检测报告的中断时间序列。根据检测日期将报告分为活动前、活动期间和活动后阶段。排除标准包括因临床原因进行的检测、已知病例的接触者以及从监狱或军队返回的检测。使用负二项式和逻辑回归模型来估计活动期间和活动后的覆盖率和阳性率变化,并对长期和周期性趋势进行了调整。
在调整了周期性和长期趋势后,活动期间(RR:0.91;95%CI:0.72 - 1.14)和活动后(RR:0.88;95%CI:0.69 - 1.11)的总体检测覆盖率均无变化。覆盖率在不同社会人口群体中有所不同,活动期间男性的检测率增加,而黑人和其他族裔群体的检测率在此阶段下降。活动期间阳性率增加(OR:1.18;95%CI 1.13 - 1.23),活动后阶段进一步增加(OR:1.40;95%CI 1.30 - 1.51)。活动期间和活动后,所有社会人口和自我报告性行为群体中检测到的衣原体感染比例均有所增加。
活动期间衣原体检测的接受度有所上升;然而,一旦考虑到检测的总体趋势,这种明显的增加并未持续。尽管如此,在控制了长期和周期性趋势后,该活动与阳性率增加相关,这与目标人群中以前不太可能前来检测的高风险个体群体检测增加有关。然而,我们的研究表明,该活动对不同人群的影响可能存在差异。应仔细制定旨在增加衣原体筛查的当前和未来信息宣传活动的内容和传播方式,使其与目标人群的所有部分相关。