National Chlamydia Screening Programme, Health Protection Agency, London, UK.
Sex Transm Infect. 2011 Jun;87(4):306-11. doi: 10.1136/sti.2010.047027. Epub 2011 Mar 22.
We compare data collected by England's National Chlamydia Screening Programme (NCSP) with national probability survey data to examine demographic and behavioural differences that may be important in understanding who the NCSP is reaching and interpreting chlamydia positivity.
Data for 538,119 men and women aged 16-24 years who were screened in 2008 and data collected from 2180 interviewees in Britain's second National Survey of Sexual Attitudes and Lifestyles 1999-2001 (Natsal-2), of whom 644 were tested for chlamydia, were compared using the χ2 statistic and logistic regression.
Compared with Natsal-2, the NCSP tested more women (67% vs. 49%). NCSP participants were more likely to be younger: 29% were 16-17 years versus 16% of men and 15% of women in Natsal-2; from ethnic minority groups: 17% of men and 14% of women versus 8% and 6%, respectively, in Natsal-2; not to have used condoms at last sex: 66% of men and 68% of women versus 48% and 63%, respectively, in Natsal-2: and more likely to report two or more partners in the last year: 62% of men and 47% of women versus 47% and 30%, respectively, in Natsal-2. In multivariate analyses, higher AOR of chlamydia positivity were found for those reporting non-use of condoms and for those reporting multiple partners in both the NCSP and Natsal-2.
The NCSP is testing young people at increased risk of chlamydia. The impact of this testing bias on the effectiveness of the programme should be evaluated.
我们将英格兰国家衣原体筛查计划(NCSP)收集的数据与全国概率调查数据进行比较,以研究可能有助于理解 NCSP 针对人群以及解释衣原体阳性的人口统计学和行为学差异。
比较了 2008 年接受筛查的 538119 名 16-24 岁男性和女性的数据,以及英国第二次全国性态度和生活方式调查(Natsal-2)中 2180 名受访者的数据,其中 644 人接受了衣原体检测,使用卡方检验和逻辑回归进行比较。
与 Natsal-2 相比,NCSP 检测了更多的女性(67%比 49%)。NCSP 参与者更年轻:29%为 16-17 岁,而 Natsal-2 中男性和女性分别为 16%和 15%;来自少数民族群体:男性和女性分别为 17%和 14%,而 Natsal-2 中分别为 8%和 6%;最近一次性行为未使用避孕套:男性和女性分别为 66%和 68%,而 Natsal-2 中分别为 48%和 63%;过去一年报告有两个或更多性伴侣的比例更高:男性和女性分别为 62%和 47%,而 Natsal-2 中分别为 47%和 30%。多变量分析发现,在 NCSP 和 Natsal-2 中报告未使用避孕套和报告多个性伴侣的人,衣原体阳性的优势比更高。
NCSP 正在对感染衣原体风险增加的年轻人进行检测。应评估这种检测偏差对该计划有效性的影响。