使用类固醇预防恰加斯病患者对苯唑哒嗪的皮肤反应。
The use of steroids to prevent cutaneous reactions to benznidazole in patients with Chagas disease.
机构信息
Division of Infectious Diseases, Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Spain.
出版信息
Pathog Glob Health. 2013 Apr;107(3):157-60. doi: 10.1179/2047773213Y.0000000081.
Abstract
The treatment of Chagas disease is limited by the frequent cutaneous side effects of benznidazole. We tested the use of steroids plus escalating doses of benznidazole to prevent this complication in 17 adult patients with chronic Trypanosoma cruzi infection and found extremely good tolerance. A randomized trial is warranted.
摘要
治疗恰加斯病受到苯硝唑频繁引起皮肤副作用的限制。我们测试了类固醇加递增剂量苯硝唑预防 17 例慢性克氏锥虫感染成年患者这种并发症，发现耐受性极好。有必要进行随机试验。
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