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利用基于网络的家族糖尿病风险信息进行糖尿病预防:一项随机对照试验。

Using web-based familial risk information for diabetes prevention: a randomized controlled trial.

机构信息

Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

BMC Public Health. 2013 May 17;13:485. doi: 10.1186/1471-2458-13-485.

DOI:10.1186/1471-2458-13-485
PMID:23683372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3711930/
Abstract

BACKGROUND

It has been suggested that family history information may be effective in motivating people to adopt health promoting behaviour. The aim was to determine if diabetic familial risk information by using a web-based tool leads to improved self-reported risk-reducing behaviour among individuals with a diabetic family history, without causing false reassurance among those without a family history.

METHODS

An online sample of 1,174 healthy adults aged 35-65 years with a BMI ≥ 25 was randomized into two groups receiving an online diabetes risk assessment. Both arms received general tailored diabetes prevention information, whilst the intervention arm also received familial risk information after completing a detailed family history questionnaire. Separate analysis was performed for four groups (family history group: 286 control versus 288 intervention group; no family history: 269 control versus 266 intervention group). Primary outcomes were self-reported behavioural outcomes: fat intake, physical activity, and attitudes towards diabetes testing. Secondary outcomes were illness and risk perceptions.

RESULTS

For individuals at familial risk there was no overall intervention effect on risk-reducing behaviour after three months, except for a decrease in self-reported saturated fat intake among low-educated individuals (Beta (b) -1.01, 95% CI -2.01 to 0.00). Familial risk information resulted in a decrease of diabetes risk worries (b -0.21, -0.40 to -0.03). For individuals without family history no effect was found on risk-reducing behaviour and perceived risk. A detailed family history assessment resulted in a greater percentage of individuals reporting a familial risk for diabetes compared to a simple enquiry.

CONCLUSIONS

Web-based familial risk information reduced worry related to diabetes risk and decreased saturated fat intake of those at greatest need of preventative care. However, the intervention was not effective for the total study population on improving risk-reducing behaviour. The emphasis on familial risk does not seem to result in false reassurance among individuals without family history. Additionally, a detailed family history questionnaire identifies more individuals at familial risk than a simple enquiry.

TRIAL REGISTRATION

NTR1938.

摘要

背景

有研究表明,家族病史信息可能有助于激励人们采取促进健康的行为。本研究旨在确定基于网络的工具提供糖尿病家族患病风险信息是否可以改善有糖尿病家族史个体的自我报告风险降低行为,同时不会给无家族史个体带来错误的安全感。

方法

本研究在线招募了 1174 名年龄在 35-65 岁、BMI≥25 的健康成年人,将他们随机分为两组,分别接受在线糖尿病风险评估。两组均收到了一般性的糖尿病预防信息,而干预组在完成详细的家族病史问卷后还收到了家族患病风险信息。对四个组(家族史组:286 名对照组与 288 名干预组;无家族史:269 名对照组与 266 名干预组)分别进行了分析。主要结局是自我报告的行为结果:脂肪摄入量、身体活动和对糖尿病检测的态度。次要结局是疾病和风险认知。

结果

对于有家族患病风险的个体,三个月后,除了低教育程度个体的自我报告饱和脂肪摄入量减少(β-1.01,95%CI-2.01 至 0.00)外,干预对降低风险行为没有总体影响。家族患病风险信息降低了糖尿病风险担忧(b-0.21,-0.40 至-0.03)。对于无家族史的个体,干预对降低风险行为和感知风险没有影响。与简单询问相比,详细的家族病史评估导致更多的个体报告有糖尿病家族患病风险。

结论

基于网络的家族患病风险信息减少了与糖尿病风险相关的担忧,并减少了高风险人群的饱和脂肪摄入量。然而,对于整个研究人群,干预措施并没有改善降低风险行为。对家族风险的强调似乎并没有给无家族史的个体带来错误的安全感。此外,详细的家族病史问卷比简单询问识别出更多有家族患病风险的个体。

试验注册

NTR1938。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8b/3711930/2ad1959d2de2/1471-2458-13-485-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8b/3711930/f34c1981bb93/1471-2458-13-485-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8b/3711930/2ad1959d2de2/1471-2458-13-485-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8b/3711930/f34c1981bb93/1471-2458-13-485-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d8b/3711930/2ad1959d2de2/1471-2458-13-485-2.jpg

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