Ridde V, Haddad S
Centre de recherche du centre hospitalier de l'université de Montréal (CRCHUM), 1058 Saint-Denis, Montréal, Quebec, Canada.
Rev Epidemiol Sante Publique. 2013 Jun;61 Suppl 2:S95-106. doi: 10.1016/j.respe.2013.03.037. Epub 2013 May 14.
Forty years ago, Schwartz and Lellouch invented pragmatic clinical trials. Their proposal has not yet been fully espoused. This appears to be the case today also in the domain of public health interventions evaluation, where some still insist on the superiority of experimental methods. Yet evaluations of complex public health interventions are fraught with pitfalls for researchers. Most such interventions take place in natural experimental contexts, where they have no control over the context or the factors that modify implementation and influence the effects. Experimental approaches are, in these cases, not very appropriate, and yet decision makers want to be able to take decisions to improve them. This article presents our experience over the past 5years with evaluative research in two public health interventions. We wish to show how we conduct evaluations in practice using a pragmatic approach. The article is focused on elements that have not, to date, received much attention in the francophone literature: the evaluability assesment and intervention logic, research strategies reinforced particularly by mixed methods and time series, and the analysis of implementation fidelity and mechanisms that foster effectiveness. Because the pragmatic approach to evaluative research stresses the need for good understanding of context and uses reinforced methodological strategies, it allows for rigorous responses to evaluation questions raised by those implementing complex public health interventions. Thus, experimental approaches are not necessarily required to analyze the effectiveness of interventions.
四十年前,施瓦茨和莱卢什发明了实用性临床试验。他们的提议尚未得到充分支持。如今在公共卫生干预措施评估领域似乎也是如此,在该领域有些人仍然坚持实验方法的优越性。然而,对研究人员来说,评估复杂的公共卫生干预措施充满了陷阱。大多数此类干预措施发生在自然实验环境中,在这种环境下,他们无法控制环境或那些会改变实施情况并影响效果的因素。在这些情况下,实验方法不太合适,但决策者希望能够做出决策来改进这些干预措施。本文介绍了我们在过去五年中对两项公共卫生干预措施进行评估研究的经验。我们希望展示我们如何在实践中采用实用性方法进行评估。本文重点关注法语文献中迄今未受到太多关注的内容:可评估性评估和干预逻辑、特别通过混合方法和时间序列强化的研究策略,以及对实施保真度和促进有效性的机制的分析。由于实用性评估研究方法强调需要很好地理解背景并使用强化的方法策略,它能够对实施复杂公共卫生干预措施的人员提出的评估问题做出严谨的回应。因此,分析干预措施的有效性不一定需要实验方法。