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心境障碍患者的情感气质和绝望感对健康和社会功能的预测:一项前瞻性随访研究。

Affective temperaments and hopelessness as predictors of health and social functioning in mood disorder patients: a prospective follow-up study.

机构信息

Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, Italy.

出版信息

J Affect Disord. 2013 Sep 5;150(2):216-22. doi: 10.1016/j.jad.2013.03.026. Epub 2013 May 17.

Abstract

BACKGROUND

Affective disorders are highly disabling illnesses constituting a significant burden for the patients, their family and the society. Therefore, it would be very useful to find tools which carefully subtype these conditions and have a strong and reliable predictive power concerning the course of illness and health and social functioning. To date, the role of hopelessness and affective temperaments in the prediction of health and social functioning and the course of affective disorders has not been studied. Thus, the aim of the present study was to assess whether affective temperaments and hopelessness, measured during hospitalization, can be useful in the prediction of global functioning (the severity of the illness and the presence and severity of psychosocial problems) at follow-up in inpatients with major depressive disorder and bipolar disorder (BD).

METHODS

The patients were 96 consecutive patients admitted to the inpatient psychiatric clinic of Sant'Andrea Hospital between January 2009 and December 2010. All patients completed the Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A) and the Beck Hopelessness Scale on admission. They were contacted on average 14 months after discharge and were asked to complete a telephone interview based on the Health of the Nation Outcome Scales (HoNOS).

RESULTS

Two patients committed suicide before the follow-up assessment. Around 77% of the patients who completed the follow-up assessment were diagnosed as BD, and around 47% reported severe hopelessness. In the multivariate analyses, a factor derived from hopelessness and hyperthymia scores and unemployment, independently predicted severity of the illness and psychosocial functioning at the follow-up.

CONCLUSIONS

Screening for the affective temperament profile and for hopelessness has importance for designing the treatment and rehabilitation plans of affective disorder patients, as these variables are involved in the course and outcome of affective disorder patients and influence their health and social functioning.

摘要

背景

情感障碍是高度致残的疾病,给患者、患者家属和社会带来了巨大负担。因此,找到能够仔细细分这些疾病,并对疾病过程、健康状况和社会功能具有强大而可靠的预测能力的工具将非常有用。迄今为止,无望感和情感气质在预测健康和社会功能以及情感障碍的病程方面的作用尚未得到研究。因此,本研究的目的是评估在住院期间测量的情感气质和无望感是否可用于预测单相和双相情感障碍住院患者在随访时的总体功能(疾病严重程度以及心理社会问题的存在和严重程度)。

方法

该研究纳入了 2009 年 1 月至 2010 年 12 月期间入住 Sant'Andrea 医院精神科病房的 96 例连续患者。所有患者在入院时均完成了 Memphis、Pisa、Paris 和 San Diego 情感气质评估量表(TEMPS-A)和贝克无望感量表。平均在出院后 14 个月与患者联系,并要求他们根据国家卫生结果量表(HoNOS)完成电话访谈。

结果

有 2 名患者在随访评估前自杀。完成随访评估的患者中约 77%被诊断为 BD,约 47%报告有严重的无望感。在多变量分析中,无望感和欣快得分以及失业的一个因子独立预测了随访时疾病的严重程度和心理社会功能。

结论

对情感气质特征和无望感进行筛查对于设计情感障碍患者的治疗和康复计划具有重要意义,因为这些变量与情感障碍患者的病程和结局有关,并影响他们的健康和社会功能。

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