Kartal Celaleddin, Fahri Aydın Esat
Private Office, Sivas, Turkey.
Department of Psychiatry, Atatürk University Medical Faculty, Erzurum, Turkey.
Psychiatry Clin Psychopharmacol. 2023 Dec 1;33(4):299-308. doi: 10.5152/pcp.2023.22597. eCollection 2023 Dec.
Functional impairment in euthymic patients with bipolar disorder is a compelling issue, and revealing unknown related factors with functional impairment is a substantial topic. We aimed to assess the effects of clinical factors, affective temperaments, and attachment on overall functioning in euthymic patients with bipolar disorder.
Sixty-three patients with bipolar disorder and 61 healthy controls participated in this study. The assessment involved Hamilton Depression Rating Scale; Young Mania Rating Scale; Relationship Scales Questionnaire; Temperament Evaluation of Memphis, Pisa, Paris, and San Diego; and Functioning Assessment Short Test.
Secure attachment scores were significantly higher in the control group than in the bipolar disorder group. Depressive, anxious, and cyclothymic temperament scores were significantly higher in the bipolar disorder group. In the bipolar disordergroup higher occupational, cognitive, autonomy, interpersonal relationships, and leisure subdomain and overall functional impairment scores were found than in the healthy control group. Secure attachment scores were significantly and negatively correlated with anxious and depressive temperaments. Secure attachment scores were positively and significantly correlated with hyperthymic temperament scores. Years of education; subclinical depressive symptoms; secure attachment; and cyclothymic, irritable, depressive, hyperthymic, and anxious temperaments were all significantly correlated with the overall functional impairment in the patient group. The cyclothymic and anxious temperament positively predicted the overall functional impairment in the bipolar group, while the secure attachment negatively predicted the overall functional impairment in the regression analysis.
The results suggest that, when following up the patients with bipolar disorder in relation to functional impairment, secure attachment, cyclothymic, and anxious temperaments should be taken into consideration.
双相情感障碍缓解期患者的功能损害是一个引人关注的问题,揭示与功能损害相关的未知因素是一个重要课题。我们旨在评估临床因素、情感气质和依恋对双相情感障碍缓解期患者整体功能的影响。
63例双相情感障碍患者和61名健康对照者参与了本研究。评估包括汉密尔顿抑郁量表、杨氏躁狂量表、关系量表问卷、孟菲斯、比萨、巴黎和圣地亚哥气质评估量表以及功能评估简短测试。
对照组的安全依恋得分显著高于双相情感障碍组。双相情感障碍组的抑郁、焦虑和环性气质得分显著更高。与健康对照组相比,双相情感障碍组在职业、认知、自主性、人际关系和休闲子领域以及整体功能损害得分更高。安全依恋得分与焦虑和抑郁气质显著负相关。安全依恋得分与轻躁狂气质得分显著正相关。受教育年限、亚临床抑郁症状、安全依恋以及环性、易怒、抑郁、轻躁狂和焦虑气质均与患者组的整体功能损害显著相关。在回归分析中,环性和焦虑气质正向预测双相情感障碍组的整体功能损害,而安全依恋负向预测整体功能损害。
结果表明,在随访双相情感障碍患者的功能损害时,应考虑安全依恋、环性和焦虑气质。