Meissner D, Hubl W, Schmidt P K
Institut für Klinische Chemie und Laboratoriumsdiagnostik, Bezirkskrankenhaus Dresden-Friedrichstadt.
Z Med Lab Diagn. 1990;31(3):181-4.
In 30 patients suffered from acute myocardial infarction the serum levels of zinc, copper, cortisol, aldosterone, and triiodthyronine were determined. Zinc and triiodthyronine decrease, the other parameters increase. The serum levels of the tested parameters show a characteristic course within the first days after onset of myocardial infarction. There are significant differences between patients without complications and patients with complicated course inclusive of deaths. The differences exist already on the day of admission. Therefore we conclude zinc, copper, cortisol, and aldosterone levels as well as the course of T3 level are useful for prognosis of the clinical progress fo AMI. The tested parameters are helpful in differential diagnosis of chest pains caused by myocardial ischemia with or without myocardial infarction. The strong correlations between trace elements and hormones show new aspects due to the explanation of pathological alterations of serum levels in clinical medicine.
对30例急性心肌梗死患者测定了血清锌、铜、皮质醇、醛固酮和三碘甲状腺原氨酸水平。锌和三碘甲状腺原氨酸水平降低，其他参数升高。所测参数的血清水平在心肌梗死发病后的头几天呈现出特征性变化过程。无并发症患者与包括死亡患者在内的病情复杂患者之间存在显著差异。入院当天就已存在差异。因此，我们得出结论，锌、铜、皮质醇和醛固酮水平以及T3水平的变化过程对急性心肌梗死临床进程的预后有帮助。所测参数有助于鉴别由心肌缺血引起的胸痛（无论有无心肌梗死）。微量元素与激素之间的强相关性为临床医学中血清水平的病理改变解释提供了新的视角。
