Lashmanova A P, Tsagareĭshvili K A
Vestn Dermatol Venerol. 1990(3):54-7.
Blood plasma and red-cell neutral lipid spectrum and red-cell phospholipid spectrum were examined in patients with eczema and psoriasis who abused and did not abuse alcohol. Time course of these parameters was studied in guinea pigs in various periods of chronic alcoholization. Chronic alcoholization was found to be associated with manifest lipid metabolism disorders, the most characteristic shifts being evaluated membrane concentration of free cholesterol and increased level of lisophosphatidylcholin, a membranotoxic agent, as well as reduction of polyunsaturated fatty acid level in phospholipids; these factors may aggravate the course of allergic dermatoses and psoriasis.
对酗酒和不酗酒的湿疹和牛皮癣患者的血浆、红细胞中性脂质谱和红细胞磷脂谱进行了检测。在豚鼠慢性酒精中毒的不同时期研究了这些参数的时间进程。发现慢性酒精中毒与明显的脂质代谢紊乱有关，最典型的变化是游离胆固醇的膜浓度升高、膜毒性剂溶血磷脂酰胆碱水平增加以及磷脂中多不饱和脂肪酸水平降低；这些因素可能会加重过敏性皮肤病和牛皮癣的病情。
