Golovin S N, Marchenko L F
Vestn Dermatol Venerol. 1990(3):9-12.
Thirty-two female patients suffering from neurodermatitis were examined. Increased hydrocortisone level and reduced estrogen concentration in the blood serum were observed during exacerbation of the condition. During remission these parameters normalized. Exacerbations were associated with marked dyslipidemia at the expense of elevated concentrations of triglycerides, free cholesterol, low-density lipoproteins in the blood serum; these parameters also showed a tendency to normalization during remission. A correlation could be traced between hormonal imbalance and disturbances of lipid metabolism regulated by these hormones. The authors emphasize the necessity of correcting dyslipidemia during exacerbation of diffuse neurodermatitis.
对32名患有神经性皮炎的女性患者进行了检查。在病情加重期间，观察到血清中氢化可的松水平升高，雌激素浓度降低。在缓解期，这些参数恢复正常。病情加重与明显的血脂异常有关，表现为血清中甘油三酯、游离胆固醇、低密度脂蛋白浓度升高；在缓解期这些参数也有恢复正常的趋势。可以发现激素失衡与受这些激素调节的脂质代谢紊乱之间存在关联。作者强调在弥漫性神经性皮炎加重期间纠正血脂异常的必要性。
